Exosomal miRNA Profiling to Identify Nanoparticle Phagocytic Mechanisms

Lin Zhang1,2,3, Changfu Hao1, Sanqiao Yao2

  • 1Department of Occupational and Environmental Health, School of Public Health, Zhengzhou University, 100 Science Avenue, Zhengzhou, 450001, China.

Summary

Downregulated exosomal microRNAs (miRNAs) hsa-let-7a-5p and hsa-let-7i-5p contribute to nanoparticle phagocytosis in pneumoconiosis by elevating WASL. This finding offers insights into nanoparticle-induced lung inflammation.

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