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Ulnar Nerve Conduction Block Using Surface Kilohertz Frequency Alternating Current: A Feasibility Study.

Shmuel Springer1, Zvi Kozol1, Zvi Reznic2

  • 1Department of Physiotherapy, Ariel University, Ariel, Israel.

Artificial Organs
|March 9, 2018
PubMed
Summary
This summary is machine-generated.

Kilohertz frequency alternating current (KHFAC) nerve stimulation reduced hand muscle activity and force. This neuromodulation technique shows potential for treating spasticity.

Keywords:
-Kilohertz frequency alternating current-Nerve blockElectrical stimulation

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Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Motor Control

Background:

  • Neuromodulation techniques are crucial for managing neurological disorders.
  • Understanding the effects of specific electrical stimulation parameters on peripheral nerves is essential for developing targeted therapies.
  • The abductor digiti minimi (ADM) muscle is a key intrinsic hand muscle involved in fine motor control.

Purpose of the Study:

  • To investigate the impact of kilohertz frequency alternating current (KHFAC) surface stimulation on the ulnar nerve.
  • To assess the effects of KHFAC stimulation on the force and myoelectrical activity of the abductor digiti minimi (ADM) muscle.
  • To explore the potential of KHFAC for neuromodulation in treating conditions like hand spasticity.

Main Methods:

  • Eighteen healthy volunteers underwent a single session of KHFAC surface stimulation (7 kHz biphasic pulse) applied to the ulnar nerve.
  • Electromyographic (EMG) activity and contraction force of the ADM muscle were measured before, immediately after, and 5 and 10 minutes post-stimulation.
  • Statistical analysis using compound adjusted z-scores was performed to evaluate changes in force and myoelectrical activity.

Main Results:

  • EMG activity of the ADM muscle decreased immediately post-stimulation, returned to baseline at 5 minutes, and decreased again at 10 minutes.
  • A significant decrease in both ADM muscle force and myoelectrical activity was observed immediately and 10 minutes after KHFAC stimulation.
  • The results indicate a temporary but significant inhibitory effect of KHFAC stimulation on intrinsic hand muscle function.

Conclusions:

  • KHFAC surface stimulation of the ulnar nerve can effectively decrease motor activity and force in intrinsic hand muscles.
  • These findings suggest KHFAC stimulation as a potential non-invasive neuromodulation tool for therapeutic applications, such as reducing hand spasticity.
  • Further research is warranted to optimize KHFAC parameters and evaluate its efficacy and safety in clinical populations.