Related Experiment Video

Updated: Feb 13, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

31.3K

Clinical features predicting group A streptococcal pharyngitis in a Japanese paediatric primary emergency medical

Masahiro Nishiyama1, Ichiro Morioka1, Mariko Taniguchi-Ikeda1

  • 11 Department of Paediatrics, 236610 Kobe University Graduate School of Medicine , Kobe, Japan.

The Journal of International Medical Research
|March 9, 2018
PubMed

Insights

Group A streptococcal (GAS) pharyngitis is rare in children under two years old. While fever and rash may suggest GAS, they are not reliable predictors for diagnosis in pediatric primary care.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Microbiology

Background:

  • Group A streptococcal (GAS) pharyngitis is a common bacterial infection in children.
  • Accurate diagnosis is crucial to prevent complications and antibiotic resistance.
  • Predictive clinical features for GAS pharyngitis in Japanese pediatric populations require further investigation.

Purpose of the Study:

  • To determine clinical indicators for predicting GAS pharyngitis in Japanese children presenting to primary emergency care.
  • To evaluate the utility of age, body temperature, presence of rash, and McIsaac score in diagnosing GAS pharyngitis.

Main Methods:

  • A retrospective analysis of 3098 pediatric patients with pharyngitis was conducted.
  • Prevalence of GAS pharyngitis was analyzed based on age and body temperature.
  • Clinical parameters, including rash and McIsaac score, were assessed for their predictive value using likelihood ratios (LRs).

Main Results:

  • GAS pharyngitis prevalence was notably low in children under 1 year (1.2%) and 1 year old (3.9%).
  • A body temperature (BT) ≥ 38.0°C did not reliably predict GAS pharyngitis (positive LR: 0.82).
  • Rash (positive LR: 1.74) and a McIsaac score of 4 or 5 (positive LR: 1.30) showed some association but were insufficient for definitive diagnosis.

Conclusions:

  • GAS pharyngitis is uncommon in infants and toddlers (<2 years).
  • Elevated body temperature (≥ 38.0°C) is not a useful predictor of GAS pharyngitis in this age group.
  • While rash and higher McIsaac scores increase suspicion, they do not confirm GAS infection, highlighting the need for diagnostic testing.

Keywords:
AgeGroup A StreptococcusMcIsaac scorebody temperaturepharyngitisrash

More Related Videos

Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis04:05

Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis

Published on: June 30, 2023

2.9K
Visualization and Analysis of Pharyngeal Arch Arteries using Whole-mount Immunohistochemistry and 3D Reconstruction10:02

Visualization and Analysis of Pharyngeal Arch Arteries using Whole-mount Immunohistochemistry and 3D Reconstruction

Published on: March 31, 2020

10.0K

Related Concept Videos

Toxidromes: Clinical Features01:30

Toxidromes: Clinical Features

Toxidromes are specific patterns of symptoms resulting from toxic substance exposure. They help in the identification and treatment of poisoning. The symptoms of each toxidrome group indicate poisoning by a certain class of chemicals or drugs.1. Sympathomimetic: Stimulates the sympathetic nervous system. Symptoms include agitation, increased heart rate (HR), blood pressure (BP), respiratory rate (RR), temperature, and pupil size. Drugs like cocaine and amphetamines, along with tremors and...
1
COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
1.9K
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
703
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
557
Pericarditis II: Clinical Features and Diagnostic Tests01:19

Pericarditis II: Clinical Features and Diagnostic Tests

Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
354
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
340