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Related Experiment Video

Updated: Feb 13, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

Endovascular revascularisation versus conservative management for intermittent claudication.

Farzin Fakhry¹, Hugo Jp Fokkenrood, Sandra Spronk

¹Departments of Epidemiology & Radiology, Erasmus MC, Dr Molewaterplein 40, PO Box 2040, Rotterdam, Netherlands, 3015 GD.

The Cochrane Database of Systematic Reviews

|March 9, 2018

Summary

Endovascular revascularisation offers moderate to large improvements in walking distance for intermittent claudication (IC) compared to no treatment. However, it shows no significant benefit over supervised exercise alone, though combination therapy may enhance outcomes.

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Last Updated: Feb 13, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

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Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication

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Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

Area of Science:

Vascular Surgery
Cardiovascular Medicine
Interventional Cardiology

Background:

Intermittent claudication (IC) is a common symptom of peripheral arterial disease, impacting mobility and quality of life.
Endovascular revascularisation is an increasingly utilized treatment for IC.

Purpose of the Study:

To systematically review the effects of endovascular revascularisation on functional performance and quality of life in patients with IC.

Main Methods:

Systematic review and meta-analysis of randomized controlled trials (RCTs).
Searched Cochrane Vascular Register and CENTRAL up to February 2017.
Assessed outcomes including maximum walking distance, pain-free walking distance, quality of life, and secondary invasive interventions.

Main Results:

Endovascular revascularisation showed moderate to large improvements in walking distances compared to no treatment.
No significant differences in functional performance or quality of life were observed when comparing endovascular revascularisation to supervised exercise alone.
Combination therapy (endovascular revascularisation plus supervised exercise or pharmacotherapy) suggested potential synergistic benefits.

Conclusions:

Endovascular revascularisation alone does not offer significant advantages over supervised exercise for IC.
Combining endovascular revascularisation with conservative therapies like supervised exercise or cilostazol may improve functional performance and quality of life.