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Updated: Feb 13, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
Differentiated thyroid cancer in childhood: a literature update
Olga Karapanou1, Marinella Tzanela2, Barbara Vlassopoulou2
1Department of Endocrinology, Diabetes and Metabolism, "Evangelismos" Hospital, Athens, Greece. olgakarapanou@yahoo.com.
Abstract:
Differentiated thyroid cancer in childhood is rare. Apart from family history, radiation exposure is a major risk factor. Although its clinical course is quite aggressive with higher rates of lymph node and pulmonary metastases as compared to adults, the final outcome tends to be favorable with mortality rates less than 2%. We herein review the clinical picture, genetic background response to treatment and recurrence rates of differentiated thyroid cancer in children and young adolescents are thoroughly reviewed and the main differences with adult differentiated thyroid cancer are highlighted.
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