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Updated: Feb 13, 2026

Biodegradable Magnesium Stent Treatment of Saccular Aneurysms in a Rat Model - Introduction of the Surgical Technique
Published on: October 1, 2017
Degradation mechanism of magnesium alloy stent under simulated human micro-stress environment
Dexue Liu1, Shiwen Hu1, Xunyan Yin1
1State Key Laboratory of Advanced Processing and Recycling of Non-ferrous Metals, Lanzhou 730050, China; School of Material Science and Engineering, Lanzhou University of Technology, Lanzhou 730050, China.
Abstract:
In this study, a vascular stent made of WE43 magnesium alloy was used as a research object and placed in a special physical simulation device constructed independently. This device provided a platform for the study of the degradation of the stent in a dynamic environment. The simulated body fluid of Hank's buffered salt solution flowing inside it would not only make the stent corroded but also apply cyclic shear stress to it, which get closer to the micro-stress environment in human blood vessels. In addition, by means of computer numerical simulation software, ANSYS Fluent 15.0, the fluid-structure interaction (FSI) model was established to simulate the wall shear stress (WSS) exerted by the flowing blood on stent in the blood vessel. Combined with the results of numerical simulation and physical simulation experiments, the degradation mechanism of magnesium alloy sent in an environment similar to the human blood vessels was studied.
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