Parietal lobe epilepsy

Vicenta Salanova1

  • 1Department of Neurology, Indiana University, Indianapolis, IN, United States.

Insights

Parietal lobe epilepsy is rare, accounting for 6% of surgically treated refractory focal epilepsy cases at the Montreal Neurological Institute. This review covers its anatomy, symptoms, and treatment outcomes.

Area of Science:

  • Neurology
  • Neurosurgery

Background:

  • Parietal lobe epilepsy is infrequently reported, representing a small percentage of refractory focal epilepsy cases.
  • The Montreal Neurological Institute reported 6% of surgically treated refractory focal epilepsy patients had epileptogenic zones in the parietal cortex.

Purpose of the Study:

  • To review the functional anatomy of the parietal lobe.
  • To discuss electroclinical manifestations and surgical outcomes for parietal lobe epilepsy.
  • To highlight recent advances in evaluating refractory focal epilepsy.

Main Methods:

  • Literature review of parietal lobe epilepsy cases.
  • Analysis of functional anatomy relevant to epilepsy.
  • Synthesis of electroclinical features and surgical outcomes.

Main Results:

  • Parietal lobe epilepsy constitutes a specific subset of refractory focal epilepsy.
  • Surgical treatment outcomes for parietal lobe epilepsy vary.
  • Advances in diagnostic techniques are improving patient evaluation.

Conclusions:

  • Parietal lobe epilepsy requires specialized understanding due to its unique characteristics.
  • Comprehensive evaluation integrating anatomical, electrophysiological, and clinical data is crucial.
  • Continued research into surgical and diagnostic advancements is essential for improving patient care.

Related Concept Videos

Lobes of the Cerebrum01:22

Lobes of the Cerebrum

The cerebral cortex, a critical structure of the brain, is intricately divided into two hemispheres, each consisting of four distinct lobes: occipital, temporal, frontal, and parietal. These lobes function cooperatively to regulate various cognitive and sensory functions, forming the basis of our complex neural capabilities.
Frontal lobe
The frontal lobes, located behind the forehead, are the command center of our brain, controlling personality, intelligence, and voluntary muscle movements....
4.8K
Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
1.4K
Atomic Orbitals02:44

Atomic Orbitals

An atomic orbital represents the three-dimensional regions in an atom where an electron has the highest probability to reside. The radial distribution function indicates the total probability of finding an electron within the thin shell at a distance r from the nucleus. The atomic orbitals have distinct shapes which are determined by l, the angular momentum quantum number. The orbitals are often drawn with a boundary surface, enclosing densest regions of the cloud.
45.2K
Hybridization of Atomic Orbitals I03:24

Hybridization of Atomic Orbitals I

The mathematical expression known as the wave function, ψ, contains information about each orbital and the wavelike properties of electrons in an isolated atom. When atoms are bound together in a molecule, the wave functions combine to produce new mathematical descriptions that have different shapes. This process of combining the wave functions for atomic orbitals is called hybridization and is mathematically accomplished by the linear combination of atomic orbitals. The new orbitals that...
67.8K
Crystal Field Theory - Tetrahedral and Square Planar Complexes02:46

Crystal Field Theory - Tetrahedral and Square Planar Complexes

Tetrahedral Complexes
Crystal field theory (CFT) is applicable to molecules in geometries other than octahedral. In octahedral complexes, the lobes of the dx2−y2 and dz2 orbitals point directly at the ligands. For tetrahedral complexes, the d orbitals remain in place, but with only four ligands located between the axes. None of the orbitals points directly at the tetrahedral ligands. However, the dx2−y2 and dz2 orbitals (along the Cartesian axes) overlap with the ligands less than the dxy,...
48.7K
Crystal Field Theory - Octahedral Complexes02:58

Crystal Field Theory - Octahedral Complexes

Crystal Field Theory
To explain the observed behavior of transition metal complexes (such as colors), a model involving electrostatic interactions between the electrons from the ligands and the electrons in the unhybridized d orbitals of the central metal atom has been developed. This electrostatic model is crystal field theory (CFT). It helps to understand, interpret, and predict the colors, magnetic behavior, and some structures of coordination compounds of transition metals.
CFT focuses on...
31.0K