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Malone appendicostomy versus cecostomy tube insertion for children with intractable constipation: A systematic review
Christine Li1, Sara Shanahan2, Michael H Livingston3
1McMaster Pediatric Surgery Research Collaborative, McMaster University, Hamilton, Ontario, Canada.
Insights
Malone appendicostomy and cecostomy tube insertion offer comparable continence rates for children with severe constipation. However, Malone appendicostomy may lead to a higher need for subsequent surgeries.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Colorectal Surgery
Background:
- Intractable constipation in children often necessitates antegrade continence enemas.
- Treatment options include Malone appendicostomy or cecostomy tube insertion.
- These procedures require surgical or minimally invasive techniques.
Purpose of the Study:
- To evaluate the comparative evidence for Malone appendicostomy versus cecostomy tube insertion in pediatric patients.
- To assess the efficacy and complication rates of these surgical interventions.
Main Methods:
- A systematic literature search was performed across Embase, Medline, CINAHL, and Web of Science.
- Included were comparative studies involving children treated with either Malone appendicostomy or cecostomy tube.
- Data extraction and study screening were conducted by two independent reviewers.
Main Results:
- Analysis of three retrospective studies (166 children) showed no significant difference in continence rates (80% vs. 70%).
- Malone appendicostomy was associated with a higher rate of additional surgeries (30% vs. 12%, p=0.01).
- Tube and stoma-related complications were reported, but quality of life was not assessed.
Conclusions:
- Malone appendicostomy and cecostomy tube insertion demonstrate similar effectiveness in achieving continence.
- Children undergoing Malone appendicostomy may face a greater likelihood of requiring further surgical intervention for complications.
Purpose:
Children with intractable constipation are often treated with antegrade continence enemas. This requires the creation of a Malone appendicostomy in the operating room or insertion of a cecostomy tube using endoscopic, radiologic, or surgical techniques. The purpose of this study was to assess the evidence regarding these procedures.
Methods:
We conducted a search of Embase, Medline, CINAHL, and Web of Science up to October 2016. We included comparative studies of children treated with Malone appendicostomy or cecostomy tube insertion. Two reviewers screened abstracts, reviewed studies, and extracted data.
Results:
We identified 166 children from three retrospective studies who underwent Malone appendicostomy (n=82) or cecostomy tube insertion (n=84). There were no differences in the number of patients who achieved continence (80% versus 70%, p=0.76), but the need for additional surgery was higher in children treated with Malone appendicostomy (30% versus 12%, p=0.01). Studies reported a variety of tube and stoma-related complications, but quality of life was not assessed using validated measures.
Conclusion:
Malone appendicostomy and cecostomy tube insertion are comparable in terms of achieving continence. Children treated with Malone appendicostomy appear to be more likely to require additional surgery due to early or late complications.
Level Of Evidence:
Therapeutic, 1c.
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