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Updated: Feb 13, 2026

Culture of Bladder Cancer Organoids as Precision Medicine Tools
08:39

Culture of Bladder Cancer Organoids as Precision Medicine Tools

Published on: December 28, 2021

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Unmasking molecular profiles of bladder cancer

Xuan-Mei Piao1, Young Joon Byun1, Wun-Jae Kim1

  • 1Department of Urology, Chungbuk National University College of Medicine, Cheongju, Korea.

Investigative and Clinical Urology
|March 10, 2018
PubMed

Insights

Precision medicine tailors treatments using individual biology. This review explores molecular profiling technologies and biomarkers for bladder cancer diagnosis and prognosis.

Area of Science:

  • Oncology
  • Genomics
  • Biomarker Discovery

Background:

  • Precision medicine shifts from "one size fits all" to personalized care.
  • This requires multi-layered molecular profiling of biomarkers for diagnosis and treatment response prediction.
  • Bladder cancer research focuses on understanding its complex molecular profiles across various biological levels.

Purpose of the Study:

  • To review current technologies for investigating molecular profiles in bladder cancer.
  • To discuss potential biomarker candidates for bladder cancer diagnosis and prognosis.

Main Methods:

  • Review of existing literature on molecular profiling technologies.
  • Analysis of studies investigating biomarkers for bladder cancer.

Main Results:

  • Multiple technologies are available for comprehensive molecular profiling (genome, epigenome, transcriptome, proteome, lipidome, metabolome).
  • Several biomarker candidates show promise for bladder cancer diagnosis and prognosis.

Conclusions:

  • Advanced molecular profiling technologies are crucial for advancing precision medicine in bladder cancer.
  • Further research into identified biomarker candidates can improve diagnostic and prognostic accuracy.
Keywords:
BiomarkersLiquid biopsyPrecision medicineUrinary bladder neoplasms

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