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Post-ERCP pancreatitis: Pathophysiology, early identification and risk stratification.

Yegor Tryliskyy1,2, Gavin J Bryce3

  • 1Clinical Surgery University of Edinburgh, Scotland, United Kingdom.

Advances in Clinical and Experimental Medicine : Official Organ Wroclaw Medical University
|March 10, 2018
PubMed
Summary

Post-ERCP pancreatitis (PEP) is a common complication. Further research is needed to improve diagnosis, risk stratification, and treatment of this condition for better patient outcomes.

Keywords:
ERCPpancreatitispost-ERCP pancreatitisrisk score

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Area of Science:

  • Gastroenterology
  • Endoscopic Procedures
  • Pancreatic Diseases

Background:

  • Acute pancreatitis is a frequent and serious complication following ERCP.
  • Understanding post-ERCP pancreatitis (PEP) is crucial for patient safety and management.

Purpose of the Study:

  • To review current knowledge on nomenclature, etiology, pathophysiology, diagnosis, and risk stratification of PEP.
  • To identify areas requiring further investigation for improved PEP management.

Main Methods:

  • A structured literature search was conducted in PubMed and Scopus.
  • Keywords included diagnosis, pathophysiology, and risk stratification of post-ERCP pancreatitis.

Main Results:

  • Multiple local and systemic factors contribute to PEP pathogenesis.
  • Patient-related risk factors aid in predicting PEP; diagnosis relies on clinical, imaging, and lab data.
  • Outpatient ERCP may be safe for selected low-risk patients.

Conclusions:

  • Further research into PEP's etio-pathogenesis is essential for enhancing diagnosis and treatment.
  • Early identification and severity stratification significantly impact patient outcomes.
  • More studies are needed to clarify risk factors, diagnosis, and treatment strategies for PEP.