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A new tremulane sesquiterpenoid from the fungus Irpex lacteus
Jian-Hai Ding1,2, Zheng-Hui Li2, Tao Feng2
1a Engineering and Technology Research Center of Liupanshan Resources, College of Chemistry and Chemical Engineering, Ningxia Normal University , Guyuan , PR China.
Natural Product Research
|March 10, 2018
Abstract:
A new tremulane sesquiterpenoid, named irlactam A (1), was isolated from cultures of the fungus Irpex lacteus. The new structure was elucidated by spectroscopic data analysis. The compound was tested for its cytotoxicities on HL-60, SMMC-7721, A-549, MCF-7, and SW480 cells and for its inhibitory activity against isozymes of 11 β-hydroxysteroid dehydrogenases (11 β-HSD).

