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Perspectives on Neuroscience
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[Personalised medicine: from a scientific perspective].

I Myin-Germeys, B W J H Penninx

    Tijdschrift Voor Psychiatrie
    |March 10, 2018
    PubMed
    Summary

    Personalized medicine requires a shift from group-based research to individual case studies. New research designs are needed to tailor therapies precisely to individual patient needs for better outcomes.

    Area of Science:

    • Personalized medicine
    • Translational research
    • Biomedical research

    Background:

    • The core objective of personalized medicine is to customize therapies to individual patient requirements.
    • A key challenge lies in transitioning from traditional group-based research to an individualized scientific approach.

    Purpose of the Study:

    • To explore scientific methodologies for advancing personalized medicine.
    • To discuss the progression from group-based findings to individual case-based science.

    Main Methods:

    • Outlining research designs applicable to personalized medicine.
    • Investigating methods for studying individual variations and tailoring interventions.

    Main Results:

    • Suggests focusing on more homogenous subgroups identified by biomarkers, sociomarkers, or psychomarkers.

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  • Proposes studying within-individual variations to precisely adjust intervention content and timing.

    • Conclusions:

    • Scientific designs for personalized medicine enhance understanding of individual patient conditions.
    • These designs facilitate the selection of optimal interventions for specific individuals.