Related Experiment Video
Updated: Feb 13, 2026

A Modified Method for Intrathecal Catheterization in Rats
Published on: February 14, 2025
An Unreported Cause of Intrathecal Baclofen Withdrawal Symptoms in a Woman With Spastic Cerebral Palsy Who Received
Sylvia A Duraski1, Anjum Sayyad
1Questions or comments about this article may be directed to Sylvia A. Duraski, MS ANP-BC CRRN CBIS, at Sylvia.duraski@nm.org. She is a Nurse Practitioner, Marianjoy Medical Group, Part of Northwestern Medicine, and Adjunct Instructor, Department of Physical Medical, Medicine and Rehabilitation, Feinberg School of Medicine, Northwestern University, Bartlett, IL. Anjum Sayyad, MD FAAPMR, is Assistant Professor, CMS; Residency Program Director; and Medical Director, Day Rehabilitation, Marianjoy Rehabilitation Hospital, Part of Northwestern Medicine, Medical Director Stroke Rehabilitation, Central Dupage Hospital, Aurora, IL.
Abstract:
This article details an unreported potential cause of withdrawal symptoms in a patient with cerebral palsy who experienced intrathecal baclofen withdrawal shortly after placement of a baclofen pump with subsequent refill with Gablofen. Initial implantation of the baclofen pump with Lioresal occurred after a successful hospital trial of intrathecal injection via lumbar puncture. However, later, the patient did experience signs and symptoms of baclofen withdrawal after a pump refill was performed with Gablofen.
More Related Videos
07:20Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy
Published on: August 9, 2024
04:33Author Spotlight: Intrathecal Injection – An Efficient and Reliable Delivery Method to Test the Efficacy of Gene Editing in Neonatal Mouse Brains
Published on: March 8, 2024
Related Concept Videos
Receiver Operating Characteristic Plot
Diabetes: Symptoms, Diagnosis, and Complications
Negative and Cognitive Symptoms of Schizophrenia
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Asthma-III: Symptoms and Complications
Classification of Asthma
Pleural Effusion II: Symptoms and Management
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
Positive Symptoms Schizophrenia: Hallucinations and Delusions
Hallucinations
Hallucinations in...