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Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis
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Contact dermatitis and patch testing for the allergist.

Luz Fonacier1, Irum Noor2

  • 1Department of Medicine, State University of New York at Stony Brook, Stony Brook, New York; Department of Allergy, New York University Winthrop Hospital, Mineola, New York.

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
|March 10, 2018
PubMed
Summary
This summary is machine-generated.

Contact dermatitis (CD) is a common skin condition. This review details key allergens and provides practical recommendations for diagnosis and management, emphasizing patch testing (PT) for allergic CD.

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Area of Science:

  • Dermatology
  • Allergology
  • Immunology

Background:

  • Contact dermatitis (CD) is a prevalent inflammatory skin condition.
  • It necessitates accurate diagnosis and management strategies for affected patients.

Purpose of the Study:

  • To review contact dermatitis (CD) and its primary allergens.
  • To offer updated recommendations for allergists in diagnosing and managing CD.

Main Methods:

  • Literature review utilizing scientific search engines like PubMed and MEDLINE.
  • Inclusion of studies focusing on CD, patch tests (PTs), key allergens, and treatment modalities.

Main Results:

  • Contact-induced dermatitis encompasses allergic, irritant, systemic, urticarial, and protein types.
  • Common allergens include metals, topical corticosteroids, fragrances, and preservatives.
  • Positive patch test (PT) relevance is determined by correlating results with patient history and examination.

Conclusions:

  • CD should be suspected in patients with various dermatitis presentations.
  • Patch testing (PT) remains the gold standard for diagnosing allergic CD.
  • The article offers practical guidance for allergists on CD diagnosis and management.