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Migraine.

David W Dodick1

  • 1Department of Neurology, Mayo Clinic, Phoenix, AZ, USA.

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|March 11, 2018
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This summary is machine-generated.

Migraine, a neurological disorder, is better understood through its genetics and neural networks. This knowledge is driving new, targeted treatments for head pain and associated symptoms.

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Area of Science:

  • Neurology
  • Neuroscience
  • Genetics

Background:

  • Migraine is a complex neurological disorder characterized by recurrent head pain and neurological symptoms.
  • Recent advances are clarifying the genetic and biological basis of migraine.
  • Understanding neural networks is crucial for developing effective treatments.

Purpose of the Study:

  • To review the clinical features and neurobiology of migraine.
  • To provide evidence for current treatment options.
  • To discuss emerging therapies for migraine management.

Main Methods:

  • Literature review of clinical features and neurobiology.
  • Evidence-based analysis of existing treatments.
  • Discussion of novel drug, device, and biological therapies.

Main Results:

  • Progress in understanding migraine's underlying mechanisms.
  • Identification of novel therapeutic targets.
  • Development of mechanism-based and disease-specific treatments.

Conclusions:

  • Fundamental understanding of migraine is advancing rapidly.
  • Novel therapeutics are emerging based on scientific progress.
  • A comprehensive review of migraine treatments is presented.