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A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
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A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

Published on: May 14, 2013

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Postoperative in-stent protrusion is an important predictor of perioperative ischemic complications after carotid

Mikiya Beppu1, Yohei Mineharu2, Hirotoshi Imamura1

  • 1Department of Neurosurgery, Kobe City Medical Center General Hospital, 2-1-1 Minatojima-Minamimachi, Chuo-ku, Kobe 650-0047, Japan.

Journal of Neuroradiology = Journal De Neuroradiologie
|March 11, 2018
PubMed

Insights

In-stent protrusion after carotid artery stenting significantly increases the risk of ipsilateral stroke. This finding highlights the importance of monitoring for in-stent protrusion to improve patient outcomes.

Area of Science:

  • Cardiovascular Medicine
  • Interventional Neurology
  • Medical Imaging

Background:

  • In-stent protrusion (ISP) following carotid artery stenting (CAS) is a recognized risk factor for thromboembolism.
  • The precise relationship between ISP and postoperative ipsilateral stroke requires further investigation.

Purpose of the Study:

  • To examine the association between in-stent protrusion and the occurrence of ipsilateral stroke within 30 days after CAS.
  • To determine if ISP is an independent risk factor for postoperative stroke.

Main Methods:

  • Retrospective analysis of 301 carotid artery lesions in 277 patients who underwent CAS.
  • In-stent protrusion was detected using intravascular ultrasound.
  • Association with 30-day postoperative ipsilateral stroke was evaluated.

Main Results:

  • In-stent protrusion was present in 15.6% of lesions, with a 30-day ipsilateral stroke rate of 8.5% in these cases.
  • Lesions without ISP had a significantly lower stroke rate (0.4%).
  • ISP remained a significant independent predictor of postoperative stroke (OR=27.03, P=0.001) after adjusting for other risk factors.

Conclusions:

  • Postoperative ipsilateral stroke occurs more frequently in patients with in-stent protrusion after CAS.
  • In-stent protrusion is a significant risk factor for stroke following carotid artery stenting.
Abstract

Keywords:
CASISPIVUSPostoperative ipsilateral strokeSymptomatic lesionsVulnerable plaque

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