Related Experiment Video

Updated: Feb 13, 2026

Immunofluorescence Analysis of Stress Granule Formation After Bacterial Challenge of Mammalian Cells
11:37

Immunofluorescence Analysis of Stress Granule Formation After Bacterial Challenge of Mammalian Cells

Published on: July 3, 2017

10.7K

Mechanism of the formation of hollow spherical granules using a high shear granulator

Takumi Asada1, Mitsunori Nishikawa2, Yasushi Ochiai1

  • 1Sumitomo Dainippon Pharma Co., Ltd., 3-45 Kurakakiuchi 1-chome, Ibaraki-shi, Osaka 567-0878, Japan.

European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences
|March 11, 2018
PubMed

Keywords:
Granulation mechanismHigh shear granulatorHollow spherical granulesX-ray computed tomography

More Related Videos

Analysis and Specification of Starch Granule Size Distributions08:46

Analysis and Specification of Starch Granule Size Distributions

Published on: March 4, 2021

5.7K
Investigating Mast Cell Secretory Granules; from Biosynthesis to Exocytosis16:01

Investigating Mast Cell Secretory Granules; from Biosynthesis to Exocytosis

Published on: January 26, 2015

13.7K

Related Concept Videos

Mechanism of Lamellipodia Formation01:31

Mechanism of Lamellipodia Formation

Cells migrating in response to external stimuli form lamellipodia, which are thin membrane protrusions supported by a mesh of linked, branched, or unbranched actin filaments. These actin filaments interact with myosin motor proteins, creating the dynamic actomyosin complex within the cytoskeleton. Contractility, or the ability to generate contractile stress, is inherent to the actomyosin complex. It helps cells detect the stiffness of the surrounding ECM and exert contractile force for...
3.8K
Spherical Coordinates01:23

Spherical Coordinates

Spherical coordinate systems are preferred over Cartesian, polar, or cylindrical coordinates for systems with spherical symmetry. For example, to describe the surface of a sphere, Cartesian coordinates require all three coordinates. On the other hand, the spherical coordinate system requires only one parameter: the sphere's radius. As a result, the complicated mathematical calculations become simple. Spherical coordinates are used in science and engineering applications like electric and...
16.2K
Mechanism of Filopodia Formation01:39

Mechanism of Filopodia Formation

Filopodia are thin, actin-rich cellular protrusions that play an important role in many fundamental cellular functions. They vary in their occurrence, length, and positioning in different cell types, suggesting their diverse roles.
Their main function is to guide migrating cells during normal tissue morphogenesis or cancer metastasis by recognizing and making initial contacts with the extracellular matrix. However, they can also act as stationary cell anchors or help to establish communication...
3.2K
Mechanisms of Membrane Domain Formation00:59

Mechanisms of Membrane Domain Formation

Different physical properties of lipids and proteins allow them to localize and form distinct islands or domains in the membrane. Some membrane domains are formed due to protein-protein interactions, whereas others are formed due to the presence of specific lipids such as sphingolipids and sterols—for example, large proteins, such as bacteriorhodopsin, aggregate and create distinct domains.
Another mechanism for membrane domain formation involves membrane proteins interacting with...
3.9K
Thin-Walled Hollow Shafts01:15

Thin-Walled Hollow Shafts

In analyzing a thin-walled hollow shaft subjected to torsional loading, a segment with width dx is isolated for examination. Despite its equilibrium state, this segment faces torsional shearing forces at its ends. These forces are quantitatively described by the product of the longitudinal shearing stress on the segment's minor surface and the area of this surface, leading to the concept of shear flow. This shear flow is consistent throughout the structure, indicating a uniform distribution of...
586
Aldehydes and Ketones with Amines: Enamine Formation Mechanism01:14

Aldehydes and Ketones with Amines: Enamine Formation Mechanism

Enamine formation involves the addition of carbonyl compounds to a secondary amine through a series of reactions. The mechanism begins with the generation of carbinolamine, a nucleophilic attack followed by several proton transfer reactions. The hydroxyl group of the carbinolamine is converted into water to make a better leaving group that can push the reaction forward by eliminating a water molecule. In enamine formation, the last step involves the abstraction of a proton from the α carbon to...
7.8K