Is Anatomic Reduction Better Than Partial Reduction in Patients with Vertical Atlantoaxial Dislocation?
Qing Wang1, Xinjie Wu2, Mingsheng Tan2
1Department of Spine Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
World Neurosurgery
|March 11, 2018
Summary
Vertical overdistraction during occipitocervical fusion for atlantoaxial dislocation may cause lower cranial nerve palsy. Revision surgery for partial reduction led to recovery of cranial nerve deficits.
Area of Science:
- Neurosurgery
- Orthopedic Surgery
- Cranial Nerve Surgery
Background:
- Vertical atlantoaxial dislocation (AAD) and basilar invagination (BI) are complex spinal conditions.
- Occipitocervical fusion (OCF) is a surgical treatment for AAD and BI.
- Lower cranial nerve (CN) palsies can be a complication of OCF.
Purpose of the Study:
- To describe lower cranial nerve (CN) palsy after OCF for vertical AAD and BI.
- To investigate the causes of CN palsy following OCF.
Main Methods:
- Retrospective case series of 4 patients with vertical AAD and BI.
- Patients underwent OCF with anatomic reduction.
- Postoperative symptoms and outcomes were analyzed.
Main Results:
- Four patients developed neurogenic dysphagia, dysarthria, and bucking postoperatively.
- Revision surgery to achieve partial reduction resulted in remarkable recovery of CN IX, X, and XI deficits.
Conclusions:
- Vertical overdistraction during OCF for AAD may cause brainstem displacement.
- This displacement can lead to traction injury of cranial nerves IX, X, and XI at the jugular foramen.
Related Concept Videos
Oxidation-Reduction Reactions
75.9K
Oxidation–Reduction Reactions
75.9K
Oxymercuration-Reduction of Alkenes
9.4K
Oxymercuration–reduction of alkenes is one of the major reactions converting alkenes to alcohols. It involves the hydration of alkenes with mercuric acetate in a mixture of tetrahydrofuran and water, forming an organomercury adduct. This is followed by a demercuration step in which the adduct is reduced to an alcohol using sodium borohydride.
9.4K
Block Diagram Reduction
574
The process of deriving the transfer function of a control system often involves reducing its block diagram to a single block. This simplification can be achieved through a series of strategic operations, including relocating branch points and comparators. These operations preserve the overall function of the system while allowing for easier manipulation and combination of blocks.
The first step in this process is the identification and relocation of a branch point. A branch point, where a...
The first step in this process is the identification and relocation of a branch point. A branch point, where a...
574
Phase I Reactions: Reductive Reactions
624
Phase I biotransformation reductive reactions are chemical processes that modify drugs by introducing or revealing polar functional groups via reduction. Enzymes called reductases catalyze these reactions, playing a pivotal role in drug metabolism by transforming lipophilic drugs into more polar, water-soluble metabolites for easy excretion. An essential type of reductive reaction is the carbonyl group reduction, where aldehydes and ketones are reduced to alcohols. An example is the...
624
Esters to Alcohols: Hydride Reductions
4.8K
Esters are reduced to primary alcohols when treated with a strong reducing agent like lithium aluminum hydride. The reaction requires two equivalents of the reducing agent and proceeds via an aldehyde intermediate.
Lithium aluminum hydride is a source of hydride ions and functions as a nucleophile. The mechanism proceeds in three steps. Firstly, the nucleophilic hydride ion attacks the carbonyl carbon of the ester to form a tetrahedral intermediate. Subsequently, the carbonyl group re-forms,...
Lithium aluminum hydride is a source of hydride ions and functions as a nucleophile. The mechanism proceeds in three steps. Firstly, the nucleophilic hydride ion attacks the carbonyl carbon of the ester to form a tetrahedral intermediate. Subsequently, the carbonyl group re-forms,...
4.8K
Alcohols from Carbonyl Compounds: Reduction
12.5K
Reduction is a simple strategy to convert a carbonyl group to a hydroxyl group. The three major pathways to reduce carbonyls to alcohols are catalytic hydrogenation, hydride reduction, and borane reduction.
Catalytic hydrogenation is similar to the reduction of an alkene or alkyne by adding H2 across the pi bond in the presence of transition metal catalysts like Raney Ni, Pd–C, Pt, or Ru. Aldehydes and ketones can be reduced by this method, often under mild to moderate heat (25–100°C) and...
Catalytic hydrogenation is similar to the reduction of an alkene or alkyne by adding H2 across the pi bond in the presence of transition metal catalysts like Raney Ni, Pd–C, Pt, or Ru. Aldehydes and ketones can be reduced by this method, often under mild to moderate heat (25–100°C) and...
12.5K


