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Updated: Feb 13, 2026

Tumor Treating Field Therapy in Combination with Bevacizumab for the Treatment of Recurrent Glioblastoma
Published on: October 27, 2014
Retroperitoneal Leydig cell tumor recurrence presenting 14 years after orchiectomy
Nicholas H Chakiryan1, Phil W Raess, Kevin Turner
1Department of Urology, Oregon Health & Science University, Portland, Oregon, USA.
Abstract:
Malignant Leydig cell tumor is a rare entity that has been previously described as rapidly progressive and uniformly fatal. We present the case of a malignant Leydig cell tumor that presented 14 years after orchiectomy with an isolated retroperitoneal metastasis. Our patient underwent a retroperitoneal lymph node dissection and has been free of recurrence or progression at 12 months of follow up. Additionally, we describe the symptomatic hormone dysfunction experienced by our patient as a result of his tumor.
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