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Published on: May 21, 2017
Anterograde percutaneous transseptal valvuloplasty in a case of severe calcific aortic stenosis
Insights
Transcatheter aortic valve stenosis treatment was achieved using an anterograde approach when retrograde catheterization failed. This novel technique successfully dilated the aortic valve in an elderly patient.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Devices
Background:
- Severe aortic stenosis poses treatment challenges, particularly in elderly patients where retrograde catheterization may be impossible.
- Percutaneous aortic valvuloplasty is a key intervention for aortic stenosis.
Observation:
- A 76-year-old woman with severe aortic stenosis could not be reached retrogradely.
- A transseptal anterograde approach was successfully employed to access the left ventricle and aortic valve.
Findings:
- The anterograde approach facilitated percutaneous aortic valvuloplasty, significantly reducing the mean aortic valvular gradient from 114 mmHg to 60 mmHg.
- The aortic valve area increased from 0.30 cm2 to 0.90 cm2 post-procedure.
- This method proved effective, yielding results comparable to standard retrograde balloon dilatation.
Implications:
- The transseptal anterograde approach offers a viable alternative for percutaneous aortic valvuloplasty when conventional retrograde methods are not feasible.
- This technique expands treatment options for elderly patients with severe aortic stenosis.
- Further research may validate this approach for a broader patient population.
Abstract:
The retrograde catheterization and percutaneous dilatation of calcific stenotic aortic valves is not always possible in elderly patients. We report the case of a 76-year old woman admitted with severe aortic stenosis in whom it was impossible to reach the left ventricle retrogradely. This led us to attempt percutaneous aortic valvuloplasty using a transseptal anterograde approach. The Mullins transseptal sheath catheter was advanced into the left ventricle and a 7 F catheter containing a long guide wire (400 cm) passed through the sheath. The flexible end of the guide wire was advanced through the aortic valve anterogradely and an angled wireloop retriever used to catch the flexible end of the guide wire and to draw it out of the body through the left femoral artery. A 7 F balloon catheter was introduced percutaneously over the long guide wire and allowed dilatation of the interatrial septum and femoral vein. A 8 F Schneider-Grüntzig catheter (80 mm) length, 19 mm diameter when inflated) was inserted anterogradely through the aortic valve over the guide wire without difficulty and the balloon catheter was inflated to a pressure of 6 atmospheres with a 30 seconds inflation-deflation cycle. Before the procedure the mean aortic valvular gradient was 114 mmHg and the aortic valve area was 0.30 cm2. After the procedure the mean aortic gradient had fallen to 60 mm Hg and the valve area had risen to 0.90 cm2. These results are comparable to those expected using the more usual retrograde balloon dilatation of the aortic valve.
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