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Updated: Feb 13, 2026

An Assay for Measuring the Activity of Escherichia coli Inducible Lysine Decarboxyase
Published on: December 19, 2010
The Cytokinin-Activating LOG-Family Proteins Are Not Lysine Decarboxylases
Muhammad Naseem1, Elena Bencurova2, Thomas Dandekar3
1Functional Genomics and Systems Biology Group, Department of Bioinformatics, Biocenter, University of Würzburg, Am Hubland, Würzburg, Germany; Systems Biology of Plant-Microbes Interaction (SPI) Lab, Department of Molecular Biology and Genetics, Bogazici University, Kuzey Park, Istanbul, Turkey; College of Natural and Health Sciences, Department of Life and Environmental Sciences, Zayed University, Abu Dhabi, UAE; These authors have equally contributed to this work.
Abstract:
A conserved PGGxGTxxE motif misleads the cytokinin (CK) converting LONELY GUY enzymes to be wrongly annotated as lysine decarboxylases (LDCs). However, so far PGGxGTxxE motif-containing LDCs do not show any LDC activity. Instead, they show phosphoribohydrolase activity by converting inactive CK nucleotides into active free-base forms to invoke CK responses.
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