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Published on: July 17, 2012
Comparison of ultrasonography and computed tomography for diagnosing diffuse thyroid disease: a multicenter study
Dong Wook Kim1, Yoo Jin Lee2, Hye Shin Ahn3
1Department of Radiology, Busan Paik Hospital, Inje University College of Medicine, 75, Bokji-ro, Busanjin-gu, Busan, 47392, South Korea. dwultra@nate.com.
Ultrasonography (US) and computed tomography (CT) both aid in detecting diffuse thyroid disease (DTD). CT showed higher sensitivity and specificity than US for diagnosing incidental DTD in surgical patients.
Area of Science:
- Radiology
- Endocrinology
- Surgical Pathology
Background:
- Incidental diffuse thyroid disease (DTD) detection requires accurate diagnostic tools.
- Preoperative imaging plays a crucial role in surgical planning and patient management.
Purpose of the Study:
- To compare the diagnostic performance of ultrasonography (US) and computed tomography (CT) for incidentally detected diffuse thyroid disease (DTD).
- To evaluate the accuracy of US and CT against histopathological results in patients undergoing thyroid surgery.
Main Methods:
- Retrospective review of 177 patients who underwent preoperative US, neck CT, and thyroid surgery.
- Radiological classification of DTD based on US and CT features.
- Comparison of imaging findings with histopathological diagnoses.
Main Results:
- Both US and CT demonstrated effectiveness in detecting DTD, with CT showing a higher area under the receiver operating characteristic curve (0.893 vs. 0.866).
- CT achieved higher sensitivity (84.4%) and specificity (84.1%) compared to US (71.9% and 91.2%, respectively) for DTD diagnosis.
- No significant difference in diagnostic performance was observed based on reader experience.
Conclusions:
- Ultrasonography and computed tomography are valuable imaging modalities for detecting incidental diffuse thyroid disease.
- CT may offer superior diagnostic performance for incidental DTD compared to US in the context of thyroid surgery.
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