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The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
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Left Atrial Appendage Occlusion: The Current Device Landscape and Future Perspectives

Ignacio Cruz-Gonzalez1, Monica Fuertes-Barahona1, Jose C Moreno-Samos1

  • 1Cardiology Department, University Hospital of Salamanca, Biomedical Research Institute of Salamanca (IBSAL), CIBER-CV, Paseo San Vicente, Salamanca 37007, Spain.

Interventional Cardiology Clinics
|March 13, 2018
PubMed

Insights

Left atrial appendage occlusion (LAAO) effectively prevents strokes in atrial fibrillation. This review covers current and emerging LAAO devices, assessing their safety and efficacy for patients.

Area of Science:

  • Cardiology
  • Medical Devices
  • Interventional Cardiology

Background:

  • Nonvalvular atrial fibrillation increases stroke risk.
  • Percutaneous left atrial appendage occlusion (LAAO) is an alternative to anticoagulation.
  • Numerous devices are available for LAAO procedures.

Purpose of the Study:

  • To review existing and novel devices for LAAO.
  • To assess the safety and efficacy of LAAO for stroke prevention.
  • To discuss the clinical data and characteristics of various LAAO devices.

Main Methods:

  • Literature review of clinical studies and device data.
  • Analysis of safety and efficacy data for LAAO devices.
  • Comparison of established and emerging LAAO technologies.

Main Results:

  • Established LAAO devices demonstrate safety and efficacy in preventing embolic strokes.
  • Newer LAAO devices show promise with ongoing clinical evaluation.
  • Emerging technologies are in preclinical or early clinical stages.

Conclusions:

  • LAAO is a proven stroke prevention strategy for nonvalvular atrial fibrillation.
  • A range of LAAO devices are available, with ongoing innovation.
  • Continued research is essential for optimizing LAAO therapies.

Keywords:
Atrial fibrillationLeft atrial appendage occlusionStrokeStroke prevention

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