Related Experiment Video
Updated: Feb 13, 2026

Isolation, Characterization, and Purification of Macrophages from Tissues Affected by Obesity-related Inflammation
Published on: April 3, 2017
Adipose tissue macrophages and their polarization in health and obesity
Leen Catrysse1, Geert van Loo1
1VIB Center for Inflammation Research, B-9052 Ghent, Belgium; Department of Biomedical Molecular Biology, Ghent University, B-9052 Ghent, Belgium.
Abstract:
Adipose tissue is a special tissue environment due to its high lipid content. Adipose tissue macrophages (ATMs) help maintain adipose tissue homeostasis in steady state by clearing dead adipocytes. However, adipose tissue changes drastically during obesity, resulting in a state of chronic low grade inflammation and a shift in the adipose immune landscape. In this review we will discuss how these changes influence the polarization of ATMs.
Related Concept Videos
Group Polarization
Obesity
Molecular Shape and Polarity
Polar Coordinates
Polarity of the Cytoskeleton
Drug Dosing: Obese Patients

