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Pantoea agglomerans Infections in Children: Report of Two Cases
Shraddha Siwakoti1, Rinku Sah1, Rupa Singh Rajbhandari2
1Department of Microbiology, B.P. Koirala Institute of Health Sciences, Dharan, Nepal.
Introduction:
Pantoea agglomerans, primarily an environmental and agricultural organism has been reported as both commensal and pathogen of humans. We present two case reports of P. agglomerans infections in children that involved the meninges and bloodstream.
Case Presentations:
A 6-month-old female baby, diagnosed as congenital hydrocephalus secondary to aqueduct stenosis with ventriculoperitoneal shunt in situ, operated 14 days back was brought to the pediatric emergency with a two-day history of high fever associated with vomiting, irritability, excessive crying, and decreased feeding. Postoperative meningitis was confirmed as cerebrospinal fluid culture revealed P. agglomerans. She responded well with a 14-day intravenous (IV) course of ceftriaxone. Also, we report a case of a 3-year-old male child referred to our center with a provisional diagnosis of UTI with chickenpox for further evaluation. During his 24-hour stay at the local hospital, he had received oral antibiotics and urinary catherization. Urine culture of catheter clamp urine was sterile. P. agglomerans was grown in blood culture. He was treated successfully with IV ceftriaxone and amikacin.
Conclusion:
P. agglomerans can cause postsurgical meningitis and bloodstream infection in children. The clinical course of infection was mild and timely administration of proper antibiotic resulted in a favorable outcome.
Insights
Pantoea agglomerans, an environmental bacterium, can cause serious infections like meningitis and bloodstream infections in children. Prompt antibiotic treatment led to favorable outcomes in these pediatric cases.
Area of Science:
- Pediatric Infectious Diseases
- Clinical Microbiology
- Bacterial Pathogenesis
Background:
- Pantoea agglomerans is typically an environmental and agricultural organism.
- It has been documented as both a commensal and pathogenic bacterium in humans.
- This study focuses on P. agglomerans infections in pediatric patients.
Observation:
- A 6-month-old infant with congenital hydrocephalus developed postoperative meningitis caused by P. agglomerans following ventriculoperitoneal shunt surgery.
- A 3-year-old male child presented with a bloodstream infection attributed to P. agglomerans, initially suspected to have a urinary tract infection and chickenpox.
Findings:
- Cerebrospinal fluid culture confirmed P. agglomerans meningitis in the infant, who responded well to intravenous ceftriaxone.
- Blood culture identified P. agglomerans in the second child, who was successfully treated with intravenous ceftriaxone and amikacin.
Implications:
- Pantoea agglomerans can be a causative agent of postsurgical meningitis and bloodstream infections in children.
- Early diagnosis and appropriate antibiotic therapy are crucial for favorable outcomes in pediatric P. agglomerans infections.
- These cases highlight the importance of considering P. agglomerans in the differential diagnosis of pediatric infections, especially in post-surgical or immunocompromised patients.
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