Pantoea agglomerans Infections in Children: Report of Two Cases

Shraddha Siwakoti1, Rinku Sah1, Rupa Singh Rajbhandari2

  • 1Department of Microbiology, B.P. Koirala Institute of Health Sciences, Dharan, Nepal.

Abstract

Insights

Pantoea agglomerans, an environmental bacterium, can cause serious infections like meningitis and bloodstream infections in children. Prompt antibiotic treatment led to favorable outcomes in these pediatric cases.

Area of Science:

  • Pediatric Infectious Diseases
  • Clinical Microbiology
  • Bacterial Pathogenesis

Background:

  • Pantoea agglomerans is typically an environmental and agricultural organism.
  • It has been documented as both a commensal and pathogenic bacterium in humans.
  • This study focuses on P. agglomerans infections in pediatric patients.

Observation:

  • A 6-month-old infant with congenital hydrocephalus developed postoperative meningitis caused by P. agglomerans following ventriculoperitoneal shunt surgery.
  • A 3-year-old male child presented with a bloodstream infection attributed to P. agglomerans, initially suspected to have a urinary tract infection and chickenpox.

Findings:

  • Cerebrospinal fluid culture confirmed P. agglomerans meningitis in the infant, who responded well to intravenous ceftriaxone.
  • Blood culture identified P. agglomerans in the second child, who was successfully treated with intravenous ceftriaxone and amikacin.

Implications:

  • Pantoea agglomerans can be a causative agent of postsurgical meningitis and bloodstream infections in children.
  • Early diagnosis and appropriate antibiotic therapy are crucial for favorable outcomes in pediatric P. agglomerans infections.
  • These cases highlight the importance of considering P. agglomerans in the differential diagnosis of pediatric infections, especially in post-surgical or immunocompromised patients.

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