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A Monoaryllead Trichloride That Resists Reductive Elimination.
Marian Olaru1, Ralf Kather1, Emanuel Hupf1
1Institut für Anorganische Chemie und Kristallographie, Universität Bremen, Leobener Straße 7, 28359, Bremen, Germany.
Angewandte Chemie (International Ed. in English)
|March 13, 2018
Summary
Researchers synthesized the first kinetically stabilized monoorganolead trihalide, RPbCl3, which resists decomposition. This breakthrough enables the creation of novel unsymmetrical diaryllead dichlorides.
Area of Science:
- Organometallic Chemistry
- Lead Chemistry
- Synthetic Chemistry
Background:
- Monoorganolead trihalides are typically unstable and prone to reductive elimination.
- Kinetic stabilization is crucial for isolating reactive organometallic compounds.
Purpose of the Study:
- To synthesize and characterize the first kinetically stabilized monoorganolead trihalide.
- To explore the utility of this stabilized compound in synthesizing unsymmetrical diaryllead dichlorides.
Main Methods:
- Transmetallation reaction between lead(IV) acetate and organomercury compounds.
- Treatment with hydrogen chloride in diethyl ether.
- Gram-scale preparation of the stabilized monoorganolead trihalide.
Main Results:
- Successful synthesis of RPbCl3 (2), the first kinetically stabilized monoorganolead trihalide.
- Demonstrated resistance of RPbCl3 to reductive elimination under ambient conditions.
- Facilitated the synthesis of unsymmetrical diaryllead dichlorides (3a-c) via gram-scale preparation of 2.
Conclusions:
- Kinetic stabilization, achieved through an intramolecularly coordinating O-donor substituent, is effective in stabilizing monoorganolead trihalides.
- The synthesized RPbCl3 serves as a valuable precursor for unsymmetrical diaryllead dichlorides.
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