Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Protein-protein Interfaces02:04

Protein-protein Interfaces

14.8K
Many proteins form complexes to carry out their functions, making protein-protein interactions (PPIs) essential for an organism's survival. Most PPIs are stabilized by numerous weak noncovalent chemical forces. The physical shape of the interfaces determines the way two proteins interact. Many globular proteins have closely-matching shapes on their surfaces, which form a large number of weak bonds. Additionally, many PPIs occur between two helices or between a surface cleft and a...
14.8K
Protein-Protein Interfaces02:04

Protein-Protein Interfaces

4.5K
4.5K
Molecules and Compounds02:38

Molecules and Compounds

69.5K
Atoms and Molecules
69.5K
Factorial Design02:01

Factorial Design

14.2K
Factorial Analysis is an experimental design that applies Analysis of Variance (ANOVA) statistical procedures to examine a change in a dependent variable due to more than one independent variable, also known as factors. Changes in worker productivity can be reasoned, for example, to be influenced by salary and other conditions, such as skill level. One way to test this hypothesis is by categorizing salary into three levels (low, moderate, and high) and skills sets into two levels (entry level...
14.2K
Group Design02:01

Group Design

10.8K
The most basic experimental design involves two groups: the experimental group and the control group. The two groups are designed to be the same except for one difference— experimental manipulation. The experimental group gets the experimental manipulation—that is, the treatment or variable being tested—and the control group does not. Since experimental manipulation is the only difference between the experimental and control groups, we can be sure that any differences between...
10.8K
Design Example: Designing a Residential Plumbing System01:25

Design Example: Designing a Residential Plumbing System

1.1K
The design of residential plumbing systems requires carefully evaluating water demand, flow rates, and pressure dynamics to ensure both efficiency and reliability. The nature of water flow within pipes is defined by its Reynolds number, which classifies flow as either laminar (smooth) or turbulent.
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum to "Enhanced fluorescence imaging guided photodynamic therapy of sinoporphyrin sodium loaded graphene oxide" [Biomaterials 42 (2015) 16442].

Biomaterials·2026
Same author

Mechanochemical Nanozyme Microbots Overcome Biofilm Barriers for Antibiotic-Free Therapy of Chronic Infections.

ACS nano·2026
Same author

Dual-pathway blockade overcomes ferroptosis resistance in pancreatic ductal adenocarcinoma via a CD133-targeted manganese-porphyrin theranostic nanoplatform.

Biomaterials·2026
Same author

Advances in multi-dimensional targeting probes for precision medicine of breast cancer.

Biomaterials·2026
Same author

Bridging functional bionanomaterials and the clinic: strategic communication as a translational enabler.

Journal of nanobiotechnology·2026
Same author

Engineering the mechano-biological properties of Zn<sub>x</sub>Fe<sub>3-x</sub>O<sub>4</sub> nanoparticles for enhanced stiffness-associated magneto-mechanical therapeutic performance.

Acta biomaterialia·2026

Related Experiment Video

Updated: Feb 13, 2026

Graphene Coatings for Biomedical Implants
13:21

Graphene Coatings for Biomedical Implants

Published on: March 1, 2013

21.8K

Graphene-based aptasensors: from molecule-interface interactions to sensor design and biomedical diagnostics.

Li Wang1, Aiguo Wu, Gang Wei

  • 1Key Laboratory of Preparation and Application of Environmental Friendly Materials (Jilin Normal University), Ministry of Education, Changchun, 130103, P. R. China. liwang_jlnu@163.com.

The Analyst
|March 13, 2018
PubMed
Summary

Graphene-based aptasensors offer enhanced sensitivity and selectivity for biomedical diagnostics. This review details their design, fabrication, and sensing applications, guiding future high-performance aptasensor development.

More Related Videos

Design to Implementation Study for Development and Patient Validation of Paper-Based Toehold Switch Diagnostics
10:42

Design to Implementation Study for Development and Patient Validation of Paper-Based Toehold Switch Diagnostics

Published on: June 17, 2022

3.5K
Fabrication of Three-Dimensional Graphene-Based Polyhedrons via Origami-Like Self-Folding
14:52

Fabrication of Three-Dimensional Graphene-Based Polyhedrons via Origami-Like Self-Folding

Published on: September 23, 2018

9.4K

Related Experiment Videos

Last Updated: Feb 13, 2026

Graphene Coatings for Biomedical Implants
13:21

Graphene Coatings for Biomedical Implants

Published on: March 1, 2013

21.8K
Design to Implementation Study for Development and Patient Validation of Paper-Based Toehold Switch Diagnostics
10:42

Design to Implementation Study for Development and Patient Validation of Paper-Based Toehold Switch Diagnostics

Published on: June 17, 2022

3.5K
Fabrication of Three-Dimensional Graphene-Based Polyhedrons via Origami-Like Self-Folding
14:52

Fabrication of Three-Dimensional Graphene-Based Polyhedrons via Origami-Like Self-Folding

Published on: September 23, 2018

9.4K

Area of Science:

  • Materials Science
  • Nanotechnology
  • Biomedical Engineering

Background:

  • Graphene nanomaterials are key components in biosensors for environmental, food, and biomedical applications.
  • Aptamers, when combined with graphene, create biofunctional nanocomposites that significantly boost biosensor sensitivity and selectivity.
  • Recent advancements focus on leveraging aptamer-graphene interactions for superior molecular recognition and biocompatibility in biosensing.

Purpose of the Study:

  • To review recent advances (2013-present) in graphene-based aptasensors for biomedical sensing.
  • To detail the design, fabrication, and sensing mechanisms of these advanced biosensors.
  • To provide guidance for developing novel, high-performance aptasensors for biological analysis.

Main Methods:

  • Comprehensive review of literature on graphene-based aptasensors.
  • Analysis of various sensing modalities including fluorescence, colorimetric, electrochemical, and others.
  • Focus on aptamer-graphene conjugation strategies and sensor architecture fabrication.

Main Results:

  • Graphene-aptamer composites demonstrate improved sensitivity and selectivity in biosensing.
  • Diverse biomedical targets like DNA, proteins, and small molecules are effectively detected.
  • Various sensing platforms (fluorescence, electrochemical, etc.) show significant performance enhancements.

Conclusions:

  • Graphene-based aptasensors represent a powerful tool for sensitive and selective biomedical detection.
  • Understanding aptamer-graphene conjugation and fabrication is crucial for optimizing sensor performance.
  • This review provides a foundation for future innovations in aptasensor technology for biological analysis.