Related Experiment Video
Updated: Feb 13, 2026

Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay
Published on: January 31, 2022
Base-Free Iron Hydrosilylene Complexes via an α-Hydride Migration that Induces Spin Pairing
Patrick W Smith1, T Don Tilley1
1Department of Chemistry , University of California, Berkeley , Berkeley , California 94720-1460 , United States.
Abstract:
Two new base-free hydrosilylene complexes of iron were synthesized using the novel starting material Cp*( iPr2MeP)FeMes. These Cp*( iPr2MeP)Fe(H)SiHR (R = DMP, Trip) complexes are in equilibrium with the corresponding iron silyl complexes, Cp*( iPr2MeP)FeSiH2R, which can be trapped and characterized for R = Trip. Unlike the Ru analogues, the Fe silylene complex with R = DMP is observed to undergo an intramolecular C-H activation involving formal addition of a benzylic C-H bond across the Fe-Si bond. This increased activity for bond activations is also observed for reactions with hydrogen, where Fe reacts faster than a Ru analog to form the hydrogenation product, Cp*( iPr2MeP)H2FeSiH2DMP.
Related Concept Videos
DNA Base Pairing
DNA Base Pairing
Base-pairing and DNA Repair
Relative Strengths of Conjugate Acid-Base Pairs
Factors Affecting α-Alkylation of Ketones: Choice of Base
The reaction involving bases like EtO− whose conjugate acid EtOH (pKa = 15.9) is stronger than the ketone (pKa = 19.2) results in an equilibrium mixture with higher ketone concentration. As a consequence,...
Base-Promoted α-Halogenation of Aldehydes and Ketones

