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Statin use in Brazil: findings and implications.

R C R M do Nascimento1,2, A A Guerra2,3, J Alvares2,3

  • 1a Post-graduated Program of Medicines and Pharmaceutical Assistance, School of Pharmacy , Federal University of Minas Gerais (UFMG) , Belo Horizonte , Minas Gerais , Brazil.

Current Medical Research and Opinion
|March 13, 2018
PubMed
Summary

This study reveals that 9.4% of Brazilian public healthcare patients use statins, primarily simvastatin. Statin use is linked to older age, higher education, and specific health conditions, highlighting potential areas for improved cardiovascular event prevention.

Keywords:
BrazilCardiovascular diseasesdrug utilizationhypercholesterolemiapharmaceutical servicesprimary healthcarestatins

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Area of Science:

  • Cardiology
  • Public Health
  • Pharmacoeconomics

Background:

  • Statins are crucial for reducing cardiovascular events.
  • Statin utilization within Brazil's public healthcare system (SUS) was previously unknown.
  • Understanding statin use is vital for optimizing cardiovascular disease management in Brazil.

Purpose of the Study:

  • To determine and characterize statin use among primary healthcare patients in Brazil's SUS.
  • To identify patient factors associated with statin use.
  • To inform future strategies for improving statin accessibility and effectiveness.

Main Methods:

  • Cross-sectional study utilizing a national representative sample from Brazil.
  • Data collected via interviews with 8803 adult patients (July 2014-May 2015).
  • Logistic regression analysis to assess associations between statin use and patient characteristics.

Main Results:

  • Prevalence of statin use was 9.4% among medicine users.
  • Simvastatin was the most common statin (90.3%).
  • Statin use associated with age (≥65), higher education, Southern residence, metabolic/heart diseases, alcohol use, and polypharmacy. Poor adherence reported by 6.5%.

Conclusions:

  • This is the first population-based study on statin use in Brazilian SUS primary care.
  • Findings highlight inequalities in access and use, guiding future research and policy.
  • Optimizing statin use is key to maximizing cardiovascular benefits in Brazil.