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Statin use in Brazil: findings and implications
R C R M do Nascimento1,2, A A Guerra2,3, J Alvares2,3
1a Post-graduated Program of Medicines and Pharmaceutical Assistance, School of Pharmacy , Federal University of Minas Gerais (UFMG) , Belo Horizonte , Minas Gerais , Brazil.
Current Medical Research and Opinion
|March 13, 2018
Summary
This study reveals that 9.4% of Brazilian public healthcare patients use statins, primarily simvastatin. Statin use is linked to older age, higher education, and specific health conditions, highlighting potential areas for improved cardiovascular event prevention.
Area of Science:
- Cardiology
- Public Health
- Pharmacoeconomics
Background:
- Statins are crucial for reducing cardiovascular events.
- Statin utilization within Brazil's public healthcare system (SUS) was previously unknown.
- Understanding statin use is vital for optimizing cardiovascular disease management in Brazil.
Purpose of the Study:
- To determine and characterize statin use among primary healthcare patients in Brazil's SUS.
- To identify patient factors associated with statin use.
- To inform future strategies for improving statin accessibility and effectiveness.
Main Methods:
- Cross-sectional study utilizing a national representative sample from Brazil.
- Data collected via interviews with 8803 adult patients (July 2014-May 2015).
- Logistic regression analysis to assess associations between statin use and patient characteristics.
Main Results:
- Prevalence of statin use was 9.4% among medicine users.
- Simvastatin was the most common statin (90.3%).
- Statin use associated with age (≥65), higher education, Southern residence, metabolic/heart diseases, alcohol use, and polypharmacy. Poor adherence reported by 6.5%.
Conclusions:
- This is the first population-based study on statin use in Brazilian SUS primary care.
- Findings highlight inequalities in access and use, guiding future research and policy.
- Optimizing statin use is key to maximizing cardiovascular benefits in Brazil.
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