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Moderate Prenatal Alcohol Exposure and Quantification of Social Behavior in Adult Rats
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What Is New in Prenatal Skeletal Dysplasias?
Teresa Victoria1, Xiaowei Zhu1, Ralph Lachman2
11 Department of Radiology, Children's Hospital of Philadelphia, 34th St and Civic Center Blvd, Philadelphia, PA 10104.
Objective:
The purpose of this article is to discuss advances in imaging and diagnosis of skeletal dysplasias.
Conclusion:
Skeletal dysplasias are a heterogeneous group of disorders affecting bone and cartilage and characterized by abnormal shape, growth, and integrity of the skeleton. These disorders may be inherited in a multitude of genetic patterns-autosomal dominant, autosomal recessive, somatic mosaic, imprinting errors of metabolism, X-linked, and teratogenic exposure. Most are monogenic diseases. The prenatal diagnosis is challenging; the findings are first seen during routine ultrasound.
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