Delivering the 48-hour antimicrobial review on inpatient drug charts

Dorian Hobday1, Aklak Choudhury2, Amani Asour3

  • 1FY2, Department of Paediatrics, Barking Havering and Redbridge University Hospitals NHS Trust, Romford, Essex RM7 0AG.

Abstract

Insights

Implementing a quality improvement project significantly enhanced the documented 48-hour antibiotic review completion rate to 100%. This improved antimicrobial stewardship was associated with a reduction in intravenous antibiotic duration.

Area of Science:

  • Healthcare Quality Improvement
  • Antimicrobial Stewardship
  • Infectious Disease Management

Background:

  • Prolonged antibiotic use increases healthcare-associated infections, resistance, and hospital stays.
  • Guidelines recommend antibiotic review between 48-72 hours, but this is often not documented.
  • Inconsistent antibiotic review practices necessitate targeted interventions.

Purpose of the Study:

  • To improve the documented completion of the 48-hour antibiotic review on inpatient drug charts.
  • To increase the percentage of completed 48-hour antimicrobial reviews to over 90%.
  • To reduce the duration of intravenous antibiotic therapy.

Main Methods:

  • A 7-week quality improvement project was conducted on two acute respiratory wards.
  • Seven interventions were implemented to enhance the completion of the 48-hour antibiotic review.
  • Primary outcomes measured were the percentage of completed 48-hour reviews and days on intravenous antibiotics.

Main Results:

  • The percentage of completed 48-hour antibiotic reviews increased from a baseline median of 68% to 100%.
  • The median number of days on intravenous antibiotics decreased from 2.25 to 1.5 days.
  • The quality improvement interventions were effective in achieving study aims.

Conclusions:

  • A simple quality improvement project significantly improved antimicrobial therapy review.
  • Improved review was associated with a significant reduction in intravenous antibiotic duration.
  • The quality improvement methodology is adaptable to other inpatient settings.

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