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[Angiosarcoma in primary lymphoedema: A rare complication].

M-M Farhat1, A Le Guern2, C Peugniez3

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Summary
This summary is machine-generated.

Stewart-Treves syndrome, a rare angiosarcoma, can develop from chronic lymphoedema. This case highlights its occurrence in the lower limb due to congenital lymphoedema, with a poor prognosis.

Keywords:
AngiosarcomaAngiosarcomeEndothelial tumorLymphœdème primairePrimary lymphedemaStewart-TrevesTumeur endothéliale

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Area of Science:

  • Oncology
  • Vascular Surgery
  • Dermatology

Background:

  • Chronic lymphoedema predisposes patients to recurrent cellulitis.
  • Stewart-Treves syndrome (STS) is a rare angiosarcoma complication of lymphoedema.
  • STS typically affects upper limbs post-mammary cancer treatment.

Observation:

  • A 69-year-old woman with 30-year history of bilateral lower limb oedema presented with painful necrotic lesions.
  • Biopsy confirmed angiosarcoma (Stewart-Treves syndrome) in the left lower limb.
  • The patient had congenital lymphoedema.

Findings:

  • Stewart-Treves syndrome developed in the lower limb secondary to congenital lymphoedema.
  • Due to extensive lesions, surgical excision was not feasible.
  • Paclitaxel chemotherapy showed a rapidly unfavorable outcome.

Implications:

  • Angiosarcoma is an exceedingly rare complication of primary lymphoedema.
  • Treatment protocols for STS in this context are not well-established.
  • The prognosis for Stewart-Treves syndrome in primary lymphoedema remains poor.