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Updated: Dec 21, 2025

Orthotopic Left Lung Transplantation in Rats
Published on: July 3, 2025
Novel Management of Atrial Septal Defect at Time of Lung Transplantation
Marian Urban1, Karen Booth2, John O'Sullivan3
1Division of Cardiothoracic Surgery, Department of Surgery, University of Nebraska Medical Center, Omaha, Nebraska.
Abstract:
We present a case of a young female patient with end-stage lung failure because of pulmonary arterial hypertension who was failing maximal medical therapy and was listed for a single sequential lung transplantation. The challenge of the case was a concomitant presence of a large atrial septal defect. The novelty of our approach was a device closure of atrial septal defect before performing transplantation with the use of intraoperative venoarterial extracorporeal membrane oxygenation.
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