Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Diabetes Mellitus: Type 2 and Gestational

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...

Diabetes Mellitus: Overview and Type I Subtype

Diabetes Mellitus: Overview and Type I Subtype

Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...

Higher Mental Functions of Brain: Learning and Memory

Higher Mental Functions of Brain: Learning and Memory

Memory is one of the most vital higher mental functions of the brain. Memory is closely related to learning because it enables us to retain information and experiences from our past to use them in our present life. It also helps us to remember facts, events, and skills, such as riding a bike or swimming. There are two types of memory — declarative memory, which involves memorizing facts or events, and procedural memory, which enables us to remember how to do something like writing or...

Alterations in Respiration II

Alterations in Respiration II

There are numerous types of normal and abnormal respiration. Based on ventilatory movements, breathing patterns are classified as regular, deep, or shallow. Examples include Biot's breathing, Cheyne-Stokes respiration, Kussmaul's breathing, hyperventilation, and hypoventilation. Each pattern is clinically significant and aids in evaluating patients.
In Biot's breathing, the respiratory rate and depth are irregular, alternating between periods of deep gasping and apnea. Common causes...

Nursing Process for Patient and Caregiver Teaching II: Planning and Implementation

Nursing Process for Patient and Caregiver Teaching II: Planning and Implementation

Planning for learning involves the development of a teaching plan. Teaching plans are similar to nursing care plans—both follow the steps of the nursing process. Planning in the teaching process involves setting goals and outcomes. Here, goals identify what a patient needs to achieve to understand a healthcare topic better, whereas the outcomes are the action to be performed by the patient to achieve the goal within a timeframe. For example, if the goal is to educate the patient about...

Nursing Process for Patient and Caregiver Teaching I: Assessment and Diagnosis

Nursing Process for Patient and Caregiver Teaching I: Assessment and Diagnosis

The nursing process provides a clinical decision-making framework for patients and families to establish and implement a personalized care plan. Since part of the nurse's duties is to teach patients, the steps of the nursing process are the most effective way to approach instruction. The nursing process and the teaching-learning process are inextricably linked.
It is critical to determine the patient's learning needs during the assessment. Determination of learning needs compounds data...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Ventral striatum temporal interference brain stimulation enhances the reward-positivity event-related potential and reduces anxiety.

NeuroImage·2026

Same author

Phantom Quantification of Magnetoencephalography Source Imaging Distortion Caused by Deep Brain Stimulation.

Brain sciences·2026

Same author

High-resolution MRI evidence for age- and sex-related changes in hippocampal subfield volume during healthy aging.

GeroScience·2026

Same author

Structure-function coupling of large-scale cortical networks across the lifespan is spectrally specific.

Communications biology·2026

Same author

Good vibrations: Sternal vibration enhances white matter density and interoceptive awareness.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology·2026

Same author

Peripheral Mitochondrial Energetics are Associated with Cortical Neurophysiological Alterations in Alzheimer's Disease.

medRxiv : the preprint server for health sciences·2026

Search research articles

Related Experiment Video

Updated: Feb 13, 2026

A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes

A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes

Published on: February 17, 2023

Altered Brain Dynamics in Patients With Type 1 Diabetes During Working Memory Processing.

Christine M Embury^1,2,3, Alex I Wiesman^1,2, Amy L Proskovec^1,2,3

¹Department of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE.

|March 14, 2018

Summary

Young adults with type 1 diabetes show altered brain activity during memory tasks, even without other health issues. Glucose management and disease duration are linked to these neural differences, suggesting early cognitive changes.

More Related Videos

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory

Published on: February 28, 2013

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

Published on: July 5, 2022

Related Experiment Videos

Last Updated: Feb 13, 2026

A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes

A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes

Published on: February 17, 2023

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory

Published on: February 28, 2013

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

Published on: July 5, 2022

Area of Science:

Neuroscience
Endocrinology
Cognitive Science

Background:

Diabetes mellitus is a known risk factor for cognitive impairment.
Mechanisms linking diabetes to cognitive decline are not fully understood.
Comorbidities often confound studies on diabetes and cognition.

Purpose of the Study:

To investigate neural processing in verbal working memory in young adults with type 1 diabetes.
To examine the relationship between neural activity and clinical diabetes measures.
To isolate the effects of type 1 diabetes on cognition, minimizing confounding factors.

Main Methods:

Magnetoencephalography (MEG) brain imaging during a verbal working memory task.
Comparison between young adults with type 1 diabetes and matched healthy controls.
Analysis of neural responses during memory encoding and maintenance phases.

Main Results:

Type 1 diabetes patients exhibited heightened neural responses in superior parietal cortices during memory encoding.
Patients showed reduced activity in parietal-occipital regions during memory maintenance.
Disease duration and glycemic control correlated significantly with neural activity patterns.

Conclusions:

Young adults with type 1 diabetes display altered neural processing in verbal working memory.
Compensatory neural mechanisms may be employed by individuals with type 1 diabetes.
Glucose management and disease duration are critical factors influencing neural function in diabetes.