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Updated: Feb 13, 2026

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Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging
Published on: November 8, 2012
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Diffusion-weighted imaging characteristics of methotrexate-induced acute encephalopathy
1Department of Hematology & Blood Transfusion Mitsui Memorial Hospital Chiyoda-ku Japan.
Clinical Case Reports
|March 14, 2018
Abstract:
Methotrexate (MTX)-induced encephalopathy is a grave complication in patients with malignancies. The early diagnosis of acute encephalopathy was difficult by conventional computed tomography (CT), and T1- or T2-weighted magnet resonance (MR) imaging. We report that the diffusion-weighted (DW) imaging is useful for early detection of acute leukoencephalopathy.
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