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Related Experiment Video

Updated: Feb 13, 2026

Imaging Cell Viability on Non-transparent Scaffolds — Using the Example of a Novel Knitted Titanium Implant
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Risk Factors for Titanium Mesh Implant Exposure Following Cranioplasty.

Talha Maqbool1,2, Adam Binhammer2, Paul Binhammer2

  • 1Faculty of Medicine, University of Toronto.

The Journal of Craniofacial Surgery
|March 14, 2018
PubMed
Summary
This summary is machine-generated.

Titanium mesh cranioplasty can lead to implant exposure, particularly after preoperative radiotherapy or free flap coverage. Soft tissue thinning over the mesh also increases exposure risk, impacting patient outcomes.

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Area of Science:

  • Neurosurgery
  • Plastic Surgery
  • Biomaterials Science

Background:

  • Titanium mesh is a common material for neurocranium reconstruction in cranioplasty.
  • Implant exposure due to overlying soft tissue erosion is a significant complication impacting patient outcomes.

Purpose of the Study:

  • To investigate potential risk factors associated with titanium mesh exposure following cranioplasty.
  • To identify factors that increase the likelihood of implant exposure and adverse patient outcomes.

Main Methods:

  • Retrospective review of consecutive patients undergoing titanium mesh cranioplasty from January 2000 to July 2016.
  • Analysis of patient demographics, management details, and outcomes.
  • Postoperative CT scans were used to assess soft tissue thickness and extradural dead space.

Main Results:

  • Eight of fifty patients (16%) experienced implant exposure or threatened exposure.
  • Preoperative radiotherapy (OR=19.67) and free flap tissue transfer (OR=6.50) were significantly associated with increased exposure risk.
  • Thinning of soft tissues over the titanium mesh was observed in 87.5% of exposed cases (OR=10.71).

Conclusions:

  • Preoperative radiotherapy, free flap coverage, and soft tissue atrophy are significant risk factors for titanium mesh exposure.
  • These findings are crucial for reconstructive surgeons to consider when using titanium mesh for cranioplasty.
  • Minimizing these risk factors may improve patient outcomes and reduce complication rates.