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Published on: March 10, 2016
Relationship between breastfeeding and asthma prevalence in young children exposed to adverse childhood experiences
Nancy E Abarca1, Aris C Garro2, Deborah N Pearlman1
1a Department of Epidemiology , Brown University, School of Public Health , Rhode Island , USA.
Insights
Breastfeeding for at least six months may prevent childhood asthma. However, this protective effect diminishes with multiple adverse childhood experiences (ACEs), suggesting ACEs may override breastfeeding benefits.
Area of Science:
- Pediatrics
- Epidemiology
- Public Health
Background:
- Childhood asthma is a significant public health concern.
- Breastfeeding is recognized for its numerous health benefits.
- The influence of adverse childhood experiences (ACEs) on chronic disease risk is increasingly studied.
Purpose of the Study:
- To examine the association between the duration of supplemental breastfeeding and asthma risk in young children.
- To investigate whether adverse childhood experiences (ACEs) modify the relationship between breastfeeding and asthma.
- To analyze asthma risk in children aged 3 to 5 years.
Main Methods:
- Utilized data from the 2011-2012 National Survey of Children's Health, a nationally representative cross-sectional survey.
- Employed modified Poisson regression models to estimate incident risk ratios (IRR) for asthma.
- Conducted stratified analyses to test for effect measure modification by ACEs.
Main Results:
- Exclusive breastfeeding (≥6 months) or supplemental breastfeeding (≥12 months) was associated with reduced lifetime asthma prevalence (IRR 0.64 and 0.68, respectively).
- Breastfeeding demonstrated a protective effect against lifetime asthma for children with one ACE.
- The protective effect of breastfeeding was attenuated in children experiencing two or more ACEs.
Conclusions:
- Exclusive and supplemental breastfeeding may prevent or delay the onset of childhood asthma.
- The protective benefits of breastfeeding against asthma may be diminished by multiple ACEs.
- Further research is needed to understand the interplay between early life adversities, breastfeeding, and asthma development.
Objective:
To investigate if duration of supplemental breastfeeding is associated with a lower asthma risk and whether adverse childhood experiences (ACEs) early in life influence this relationship in children ages 3 to 5 years.
Methods:
Data were from the 2011-2012 National Survey of Children's Health, a nationally representative cross-sectional survey. Modified Poisson regression models were used to estimate incident risk ratios (IRR) for lifetime and current asthma in young children aged 3 to 5 years (n = 15,642). We tested for effect measure modification using stratified analyses.
Results:
Exclusive breastfeeding for at least 6 months or supplemental breastfeeding for children ≥12 months significantly reduced the risk of lifetime asthma prevalence compared to never breastfed children (IRR 0.64; 95% CI: 0.46-0.88, p = 0.007; and IRR 0.68; 95% CI: 0.47-0.99, p = 0.044, respectively), adjusted for covariates. In stratified analyses, breastfeeding reduced the risk of lifetime asthma for children who experienced 1 ACE but not for children who experienced 2 or more ACEs.
Conclusion:
Exclusive breastfeeding for at least 6 months, with and without supplementation, appears to prevent asthma or delay its onset. The protective effect of breastfeeding was attenuated among children who experienced more than 2 ACEs. The known harmful effects that ACEs have on children's health may outweigh the benefits of breastfeeding in reducing the risk of a child developing asthma. Understanding how specific time periods in a child's life may be most affected by exposure to early life adversities, along with the protective effect of breastfeeding against asthma, are important areas of further study.
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