Sanjad-Sakati Syndrome: Oral Health Care.

Area of Science:

• Dentistry
• Genetics
• Pediatrics

Background:

• Sanjad-Sakati syndrome is a rare genetic disorder characterized by intellectual disability, growth retardation, and distinctive facial features.
• Orofacial manifestations are common in Sanjad-Sakati syndrome, impacting oral health and function.

Observation:

• The patient exhibited microcephaly, thin lips, a beaked nose, low-set ears, and a retrognathic mandible.
• Oral findings included oligodontia/hypodontia, small dental arches, a high-arched palate, deep overbite, and increased overjet.

Findings:

• The case highlights the specific orofacial phenotype associated with Sanjad-Sakati syndrome.
• Dental rehabilitation involved prosthetic crowns, stainless steel crowns, and removable partial prostheses to address missing teeth and malocclusion.

Implications:

• Early recognition of orofacial features can aid in the diagnosis of Sanjad-Sakati syndrome.
• Multidisciplinary dental management is essential, considering potential complications from intellectual, neurological, and endocrine abnormalities in affected children.