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Updated: Feb 13, 2026

In Vivo Canine Muscle Function Assay
Published on: April 5, 2011
The Effect of Tibial Plateau Levelling Osteotomy on Stifle Extensor Mechanism Load: A Canine Ex Vivo Study
Jarrod O Drew1, Mark R Glyde1, Giselle L Hosgood1
1School of Veterinary and Life Sciences, Murdoch University, Murdoch, Western Australia, Australia.
Objective:
To evaluate the effect of tibial plateau levelling osteotomy on stifle extensor mechanism load in an ex vivo cruciate-intact canine cadaveric model.
Study Design:
Ex vivo mechanical testing study.
Animals:
Cadaveric canine pelvic limbs (n = 6).
Materials And Methods:
A 21-mm tibial radial osteotomy was performed on pelvic limbs (n = 6) prior to being mounted into a load-bearing limb press. The proximal tibial segment was incrementally rotated until the anatomical tibial plateau angle had been rotated to at least 1°. The proportional change in stifle extensor mechanism load between the anatomical tibial plateau angle and the neutralized (∼6.5 degrees) and over-rotated (∼1°) tibial plateau angle was analysed using a one-sample t-test against a null hypothesis of no change. A p-value ≤0.05 was considered significant.
Results:
There was no significant change in the stifle extensor mechanism load from the anatomical tibial plateau angle (308 N [261-355 N]) to the neutralized tibial plateau angle (313 N [254-372 N]; p =.81), or from the anatomical tibial plateau angle to the over-rotated tibial plateau angle (303 N [254-352 N; p = 0.67).
Conclusion:
Tibial plateau levelling osteotomy does not significantly alter stifle extensor mechanism load at either a neutralized or over-rotated tibial plateau angle in our cruciate-intact model.
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