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Multifractal Spectrum Analysis for Assessing Pulmonary Nodule Malignancy
Published on: January 10, 2025
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Interventional bronchoscopy in malignant central airway obstruction by extra-pulmonary malignancy
Beomsu Shin1, Boksoon Chang2, Hojoong Kim3
1Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, South Korea.
BMC Pulmonary Medicine
|March 15, 2018
Summary
Interventional bronchoscopy offers a safe and effective treatment for malignant central airway obstruction (MCAO) from extra-pulmonary cancers. Identifying prognostic factors can help select patients who will benefit most from this procedure.
Area of Science:
- Pulmonology
- Oncology
- Interventional Radiology
Background:
- Malignant central airway obstruction (MCAO) is often treated with interventional bronchoscopy.
- Limited data exists on interventional bronchoscopy for MCAO caused by extra-pulmonary malignancies.
Purpose of the Study:
- To evaluate treatment outcomes of interventional bronchoscopy for MCAO due to extra-pulmonary malignancy.
- To identify prognostic factors influencing survival after bronchoscopic intervention in these patients.
Main Methods:
- Retrospective analysis of 98 patients with MCAO from extra-pulmonary malignancy.
- Interventional bronchoscopy procedures performed between 2004 and 2014.
- Data collection on primary cancer site, intervention techniques, success rates, complications, and survival.
Main Results:
- Esophageal cancer was the most common primary site (37.9%).
- Common interventions included mechanical debulking (84.7%), stent insertion (70.4%), and laser cauterization (37.8%).
- Technical success was 89.9%, with 20.4% acute complications and 3.1% procedure-related deaths. Survival was reduced in patients with MCAO from cancers other than thyroid or lymphoma, mixed lesions, or those not receiving adjuvant treatment.
Conclusions:
- Bronchoscopic intervention is a safe and effective option for MCAO from end-stage extra-pulmonary malignancies.
- Prognostic factors for poor survival were identified, aiding in patient selection for bronchoscopic intervention.
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