Related Experiment Video
Updated: Feb 13, 2026

High-definition Transcranial Direct Current Stimulation over Right Dorsolateral Prefrontal Cortex to Enhance Metacognitive Sensitivity
Published on: September 26, 2025
Exploring the effects of anodal and cathodal high definition transcranial direct current stimulation targeting the
Wing Ting To1, Justin Eroh2, John Hart2
1The University of Texas at Dallas, School of Behavioral and Brain Sciences, 800 West Campbell Road, Texas, 75080, USA. wingting.to@utdallas.edu.
Abstract:
The dorsal anterior cingulate cortex (dACC) has been identified as a core region affected by many disorders, representing a promising target for neuromodulation. High Definition-transcranial Direct Current Stimulation (HD-tDCS) is a non-invasive neuromodulation technique that has already shown promising outcomes and has been tested to engage deeper structures. This study investigates whether it is possible to modulate dACC activity using anodal and cathodal HD-tDCS. Furthermore, it examines what effects anodal and cathodal HD-tDCS targeting dACC have on cognitive and emotional processing. Forty-five healthy subjects were randomly assigned to 1 of 3 groups: anodal, cathodal, and sham. Resting-state electroencephalography (rsEEG) and a cognitive and emotional Counting Stroop task were administered before and after HD-tDCS. RsEEG showed changes: anodal HD-tDCS showed significant increase in beta frequency band activity in dACC, while cathodal HD-tDCS led to significant increase in activity at dorsal and rostral ACC in the theta frequency band. Behavioral changes were also found after anodal HD-tDCS in the cognitive Counting Stroop for incongruent trials and after cathodal HD-tDCS in the emotional Counting Stroop for emotional trials. This study demonstrated that HD-tDCS is able to modulate dACC activity, suggesting that it has the potential to be used as a treatment tool.
More Related Videos
15:05Technique and Considerations in the Use of 4x1 Ring High-definition Transcranial Direct Current Stimulation HD-tDCS
Published on: July 14, 2013
07:20Stimulation Location Determination using a 3D Digitizer with High-Definition Transcranial Direct Current Stimulation
Published on: December 20, 2019
Related Concept Videos
Directing and Steric Effects in Disubstituted Benzene Derivatives
Definite Integral
Definition of z-Transform
Properties of Definite Integral I
The Precise Definition of a Limit
Properties of Definite Integral II