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A novel image processing procedure for thermographic image analysis.

Sara Matteoli1, Davide Coppini2, Andrea Corvi2

  • 1Department of Industrial Engineering, University of Florence, via di S. Marta 3, 50139, Florence, Italy. sara.matteoli@unifi.it.

Medical & Biological Engineering & Computing
|March 15, 2018
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Summary
This summary is machine-generated.

A new thermographic imaging method accurately measures ocular surface temperature (OST) and creates thermal maps. This reliable technique is geometry-independent, enabling comparisons across individuals and populations for clinical applications.

Keywords:
NormalizationOcular diseaseOcular profileOcular surface temperature

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Biomedical Engineering

Background:

  • Ocular surface temperature (OST) measurement is crucial for diagnosing various eye conditions.
  • Existing methods for OST assessment can be limited by ocular geometry and reproducibility.
  • Thermography offers a non-invasive approach to visualize thermal patterns on the ocular surface.

Purpose of the Study:

  • To develop and validate a novel, fast, reliable, and reproducible imaging procedure for processing thermographic images of the ocular surface.
  • To assess the intra- and inter-examiner repeatability of the developed ocular thermography method.
  • To demonstrate the clinical applicability of the method by analyzing thermal maps in healthy and diseased eyes.

Main Methods:

  • Development of a thermographic imaging procedure for ocular surface temperature (OST) measurement and thermal map generation.
  • Application of the procedure to healthy subjects and patients with ocular malignant lesions.
  • Evaluation of repeatability using coefficients of repeatability (COR) for intra- and inter-examiner variability.
  • Statistical analysis (P-value) to compare OST between healthy eyes and eyes with lesions.

Main Results:

  • The developed procedure demonstrated high repeatability, with small intra-examiner (%COR 0.06-0.80) and inter-examiner variability (%COR 0.03-0.94).
  • OST measurements and thermal maps accurately reflected the clinical status of the investigated eyes.
  • A statistically significant difference in OST was observed between the affected eye (warmer) and the contralateral eye in a patient with an ocular malignant lesion (P < 0.0001).
  • No significant OST difference was found between the right and left eyes in a healthy subject (P = 0.25).

Conclusions:

  • The novel ocular thermography procedure is simple, immediate, modular, and generic, making it suitable for diverse clinical applications.
  • The geometry-independent nature of the method allows for robust comparisons of ocular thermal profiles.
  • This validated thermographic technique provides a reliable tool for objective assessment and monitoring of ocular conditions.