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Updated: Feb 13, 2026

Cerenkov Luminescence Imaging of Interscapular Brown Adipose Tissue
Published on: October 7, 2014
Localization-controlled two-color luminescence imaging via environmental modulation of energy transfer in a
Paola Bonaccorsi1, Teresa Papalia, Anna Barattucci
1Department of Chem. Biol. Pharm. & Environ. Sciences, University of Messina, Via F. Stagno d'Alcontres 31, Messina, Italy. pbonaccorsi@unime.it campagna@unime.it fpuntoriero@unime.it.
Abstract:
We prepared a bichromophoric species 1, made of two different bodipy dyes bridged by a d-galactose unit. 1 exhibits different emission spectra when located in different compartments of biological systems, independently of its concentration. This is an unprecedented feature for a single multicomponent molecule and is due to the dependence on the environment of the photoinduced energy transfer process occurring between its bodipy subunits. Therefore, 1 can give useful information about cell composition and ultimately anomalies without requiring the simultaneous use of several different compounds, paving the way for the use of environment-controlled inter-component energy transfer to gain cell information based on luminescence imaging.
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