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Updated: Feb 13, 2026

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart
Published on: May 11, 2018
The Effects of Hemodynamic Unloading in African Americans Implanted with Left Ventricular Assist Devices
David M Tehrani1, Daniel Rodgers1, Sirtaz Adatya2
1From the Division of Cardiology, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois.
Abstract:
We aim to evaluate the echocardiographic/hemodynamic effects of left ventricular assist devices in African American (AA) versus non-AA patients undergoing ramp speed optimization and its subsequent effect on readmissions. In 65 patients (26 AA), no differences in baseline echocardiographic/hemodynamic parameters were noted. During ramp testing, there was a significantly greater increase in cardiac output (slope: 0.29 ± 0.24 vs. 0.15 ± 0.12, p < 0.01) with more rapid decrease in left ventricular end-diastolic diameter (slope: -0.21 ± 0.14 vs. -0.13 ± 0.07 L/min, p < 0.01) in the AA group. AAs had higher all-cause, but similar heart failure readmission rate as compared with the non-AA group.
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