Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Long-term Depression

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.

Trigonometric Functions of Real Numbers

Trigonometric Functions of Real Numbers

The unit circle—a circle with a radius of one, centered at the origin of the coordinate plane—serves as the foundational framework for defining trigonometric functions. In this context, arc length refers to the distance measured along the circumference of the circle between two points, and it provides a way to represent real numbers geometrically. Each real number t corresponds to an arc length measured counterclockwise from the positive x-axis around the circle. The coordinates of...

Design Example: Strain Gauge Bridge or Wheatstone Bridge

Design Example: Strain Gauge Bridge or Wheatstone Bridge

The utilization of strain gauges as transducers for converting mechanical strain into electrical signals is a common practice in various engineering applications. These strain gauges are frequently integrated into Wheatstone bridge circuits to accurately measure parameters such as force or pressure. Within this context, each element within the circuit exhibits a resistance that undergoes subtle variations when subjected to mechanical strain. The primary objective is to convert minuscule...

Wheatstone Bridge

Wheatstone Bridge

An ohmmeter is a resistance-measuring device. It works by applying a voltage to a resistor of unknown resistance and measuring the current across the resistor. The resistance value is deduced using Ohm's law. Usually, the standard configuration of an ohmmeter comprises a voltmeter or an ammeter. However, such configurations are limited in accuracy because the meters alter the voltage applied to the resistor and the current that flows through it.
Thus, for accurate resistance measurements, a...

Bridge rectifier

Bridge rectifier

The bridge rectifier is essential in electronics for efficiently converting alternating current (AC) to direct current (DC). Comprised of four diodes configured in a bridge layout, this rectifier effectively processes both the positive and negative halves of the AC waveform, making it superior to half-wave and full-wave center-tapped rectifiers in terms of voltage regulation and output stability.
Operationally, the bridge rectifier allows current flow through two of its diodes during each...

Gap Junctions

Gap Junctions

Multicellular organisms employ a variety of ways for cells to communicate with each other. Gap junctions are specialized proteins that form pores between neighboring cells in animals, connecting the cytoplasm between the two, and allowing for the exchange of molecules and ions. They are found in a wide range of invertebrate and vertebrate species, mediate numerous functions including cell differentiation and development, and are associated with numerous human diseases, including cardiac and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Brain Structures and Cognitive Decline: Moderation Analysis of the PACt-MD Randomized Clinical Trial of Brain Stimulation Plus Cognitive Remediation in Older Adults With Remitted Depression or Mild Cognitive Impairment.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry·2026

Same author

A qualitative exploration of intimacy, romance, and sexuality in early psychosis: needs, barriers, and associations with recovery.

Journal of mental health (Abingdon, England)·2026

Same author

Drug Development.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025

Same author

Public Health.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025

Same author

Therapeutic Improvement in People With Schizophrenia Undergoing tACS/CBTp (Transcranial Alternating Current Stimulation/Cognitive Behavioral Therapy for Psychosis) Associated With Usual Medication Regimen: Protocol for a Pilot, Randomized, Single-Blind Trial.

JMIR research protocols·2025

Same author

E-Cog: An online training platform for cognitive health interventions based on the ADDIE model.

Digital health·2025

Search research articles

Related Experiment Video

Updated: Feb 13, 2026

Transplantation of Schwann Cells Inside PVDF-TrFE Conduits to Bridge Transected Rat Spinal Cord Stumps to Promote Axon Regeneration Across the Gap

Transplantation of Schwann Cells Inside PVDF-TrFE Conduits to Bridge Transected Rat Spinal Cord Stumps to Promote Axon Regeneration Across the Gap

Published on: November 3, 2017

Self Efficacy in Depression: Bridging the Gap Between Competence and Real World Functioning.

Melissa Milanovic, Emma Ayukawa, Aleksandra Usyatynsky

The Journal of Nervous and Mental Disease

|March 15, 2018

Summary

In major depressive disorder (MDD), self-efficacy significantly impacts real-world functioning, bridging the gap between ability and performance in daily adaptive and interpersonal tasks, even when accounting for depressive symptoms.

More Related Videos

Author Spotlight: Exercise Test for Evaluation of the Functional Efficacy of the Pig Cardiovascular System

Author Spotlight: Exercise Test for Evaluation of the Functional Efficacy of the Pig Cardiovascular System

Published on: May 12, 2023

An R-Based Landscape Validation of a Competing Risk Model

An R-Based Landscape Validation of a Competing Risk Model

Published on: September 16, 2022

Related Experiment Videos

Last Updated: Feb 13, 2026

Transplantation of Schwann Cells Inside PVDF-TrFE Conduits to Bridge Transected Rat Spinal Cord Stumps to Promote Axon Regeneration Across the Gap

Transplantation of Schwann Cells Inside PVDF-TrFE Conduits to Bridge Transected Rat Spinal Cord Stumps to Promote Axon Regeneration Across the Gap

Published on: November 3, 2017

Author Spotlight: Exercise Test for Evaluation of the Functional Efficacy of the Pig Cardiovascular System

Author Spotlight: Exercise Test for Evaluation of the Functional Efficacy of the Pig Cardiovascular System

Published on: May 12, 2023

An R-Based Landscape Validation of a Competing Risk Model

An R-Based Landscape Validation of a Competing Risk Model

Published on: September 16, 2022

Area of Science:

Psychiatry
Clinical Psychology
Behavioral Science

Background:

Major depressive disorder (MDD) is often associated with a discrepancy between an individual's perceived competence and their actual real-world performance.
This gap in functioning can affect adaptive and interpersonal behaviors, impacting daily life.
Understanding the factors that influence this discrepancy is crucial for effective treatment.

Purpose of the Study:

To investigate the discrepancy between competence and real-world functioning in adaptive and interpersonal behaviors among individuals with MDD.
To determine if self-efficacy significantly predicts this discrepancy, independent of depressive symptom severity.
To explore the role of self-efficacy in the deployment of functional skills in individuals with MDD.

Main Methods:

Forty-two participants diagnosed with MDD were recruited from mental health clinics.
Evaluated competence, self-efficacy, and real-world functioning across adaptive and interpersonal domains.
Assessed depressive symptoms using the Beck Depression Inventory II and employed hierarchical regression analysis.

Main Results:

Self-efficacy emerged as a significant predictor of functioning in both adaptive and interpersonal domains, beyond the influence of depressive symptoms.
Interpersonal self-efficacy specifically accounted for significant variance in the discrepancy between interpersonal competence and real-world functioning.
The study provides novel, multilevel data on the interplay of competence, functioning, and self-efficacy in MDD.

Conclusions:

Self-efficacy plays a critical role in enabling individuals with MDD to translate their skills into effective real-world performance.
Interventions aimed at enhancing self-efficacy may improve adaptive and interpersonal functioning in major depressive disorder.
This research highlights the importance of a multidimensional approach to understanding functional deficits in MDD.