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Related Concept Videos

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In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
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Periodontitis and Rheumatoid Arthritis: A Review.

P M Bartold1, R I Marshall2, D R Haynes3

  • 1Department of Dentistry, University of Adelaide, Adelaide, South Australia, Australia.

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|March 15, 2018
PubMed
Summary
This summary is machine-generated.

Rheumatoid arthritis (RA) and periodontitis share common inflammatory pathways. Patients with RA often have worse periodontal disease, highlighting the need for dental screening in RA patients.

Keywords:
Arthritis, rheumatoidperiodontitis

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Area of Science:

  • Immunology
  • Periodontology
  • Rheumatology

Background:

  • Periodontitis and rheumatoid arthritis (RA) are chronic inflammatory conditions.
  • Emerging evidence suggests a significant association between the severity of periodontal disease and RA.
  • Both conditions may stem from common underlying inflammatory dysfunctions.

Purpose of the Study:

  • To explore the shared pathological mechanisms between periodontitis and RA.
  • To review the current evidence linking periodontal disease and rheumatoid arthritis.
  • To discuss the clinical implications of this relationship.

Main Methods:

  • Literature review of studies investigating the link between periodontitis and RA.
  • Analysis of common pathological features and inflammatory pathways.
  • Synthesis of evidence on the relationship between disease severity and extent.

Main Results:

  • A strong correlation exists between the extent/severity of periodontal disease and RA.
  • Individuals with advanced RA are more prone to severe periodontal issues, and vice versa.
  • Both diseases appear to result from an imbalance in pro-inflammatory and anti-inflammatory cytokines.

Conclusions:

  • Periodontitis and RA are closely related through shared inflammatory mechanisms.
  • Future treatments may target pro-inflammatory cytokines and proteases for both conditions.
  • Routine periodontal screening is recommended for patients diagnosed with rheumatoid arthritis.