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Gender difference in the association between brachial-ankle pulse wave velocity and cardiovascular risk scores

Tae-Min Rhee1,2, Hack-Lyoung Kim1,2, Sohee Oh3

  • 1Department of Internal Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Korea.

The Korean Journal of Internal Medicine
|March 16, 2018
PubMed

Insights

Brachial-ankle pulse wave velocity (baPWV) moderately correlates with cardiovascular risk scores in Koreans. This association is stronger in women, suggesting baPWV may better predict cardiovascular risk in healthy women.

Area of Science:

  • Cardiovascular Medicine
  • Biomedical Engineering
  • Public Health

Background:

  • Brachial-ankle pulse wave velocity (baPWV) is a validated method for assessing cardiovascular risk.
  • The relationship between baPWV and traditional cardiovascular risk scores requires further elucidation.
  • This study examines baPWV's correlation with established risk scores in diverse populations.

Purpose of the Study:

  • To investigate the correlation between baPWV and four distinct cardiovascular risk scores.
  • To compare the strength of this correlation between men and women.
  • To assess the utility of baPWV in predicting cardiovascular risk in a healthy population.

Main Methods:

  • Retrospective analysis of 539 subjects without cardiovascular disease (CVD).
  • baPWV measurements and calculation of four cardiovascular risk scores: Framingham risk score (FRS), Adult Treatment Panel (ATP) III revised FRS, generalized FRS, and American College of Cardiology/American Heart Association (ACC/AHA) CVD risk.
  • Statistical analysis to determine correlations and gender-based differences.

Main Results:

  • Moderate positive correlations were observed between baPWV and all four risk scores in the total population (r = 0.571–0.594, p < 0.001).
  • Correlations were significantly stronger in women compared to men for all risk scores (e.g., FRS: r = 0.649 in women vs. 0.451 in men).
  • Gender differences in correlation strength were statistically significant (p ≤ 0.005).

Conclusions:

  • baPWV shows a moderate positive correlation with multiple cardiovascular risk scores in middle-aged and elderly Koreans without CVD.
  • The correlation between baPWV and cardiovascular risk scores is notably stronger in women than in men.
  • These findings suggest that baPWV may be a more effective tool for predicting cardiovascular risk in healthy women.
Abstract

Keywords:
Cardiovascular diseasesPulse wave analysisRisk assessmentSex characteristics

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