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Updated: Feb 13, 2026

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
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Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

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A non-conserved amino acid variant regulates differential signalling between human and mouse CD28

Nicla Porciello1, Paola Grazioli2, Antonio F Campese3

  • 1Department of Biology and Biotechnology Charles Darwin, Laboratory Affiliated at Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University, 00185, Rome, Italy.

Nature Communications
|March 16, 2018
PubMed

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