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Updated: Feb 13, 2026

Author Spotlight: Development and Evaluation of a Compound Acne Rodent Model Using C. acnes and Oleic Acid
Published on: November 1, 2024
Light Therapies for Acne
Pawel Posadzki1, Josip Car1,2
1Centre for Population Health Sciences (CePHaS), Lee Kong Chian School of Medicine, Novena Campus, Nanyang Technological University, Singapore.
Clinical Question:
Are light therapies effective and safe for treating acne?
Bottom Line:
The evidence for all light therapies remains weak and inconclusive. Red-light methyl aminolevulinate-photodynamic therapy (MAL-PDT) was the only treatment associated with a small though clinically insignificant reduction in the number of inflamed lesions and in global improvement as assessed by an investigator in moderate to severe acne. Red-light MAL-PDT was not associated with higher rates of severe adverse effects than placebo or no treatment. Owing to inadequate reporting of adverse effects such as scarring or blistering, the safety of all light therapies remains uncertain.
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